Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
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In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
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Supramolecular and dynamic covalent hydrogel scaffolds: from gelation chemistry to enhanced cell retention and cartilage regeneration
TL;DR: The most recent progress in the gelation strategies of biomedical supramolecular and DCC hydrogels are highlighted and their applications for enhancing cell retention and cartilage/osteochondral regeneration are focused on.
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Recent progress in polymer hydrogel bioadhesives
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A shape memory and antibacterial cryogel with rapid hemostasis for noncompressible hemorrhage and wound healing
Ahmet Raşit ORHAN,Longtao Yao,Huichang Gao,Dayane Gomes Barros Balaban,Zefeng Lin,Qiyuan Dai,Shuangli Zhu,Shuxian Li,Cong Liu,Qi Feng,Qingtao Li,Gang Wang,Xiaofeng Chen,Xiaodong Cao +13 more
TL;DR: In this paper, a shape memory cryogel was prepared through mixing quaternized chitosan (QCS) and mesoporous bioactive glass (MBG) under −20°C, in which MBG could activate intrinsic coagulation pathway and endow the shapeogel with the function for promoting wound healing.
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Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing.
TL;DR: The results of in vitro and in vivo studies revealed that the prepared antibacterial hydrogels could largely inhibit bacterial growth and have great potential in chronic wound healing applications, such as severe wound cure and treatment of open trauma infections.
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Doubly crosslinked biodegradable hydrogels based on gellan gum and chitosan for drug delivery and wound dressing.
Xiaomin Zhang,Yajin Pan,Shengke Li,Lian Xing,Shoukang Du,Guoliang Yuan,Jianliang Li,Tianle Zhou,Dangsheng Xiong,Huaping Tan,Zhonghua Ling,Yong Chen,Xiaohong Hu,Xiaohong Niu +13 more
TL;DR: The results support the bioactive composite hydrogel can be employed as a promising injectable scaffold for promoting wound regeneration and drug delivery.
References
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Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
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Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.