Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
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In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
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Injectable supramolecular nanohydrogel from a micellar self-assembling calix[4]arene derivative and curcumin for a sustained drug release.
TL;DR: The nanohydrogel which combines the mechanical properties of a hydrogel and the benefits of a nanoscale micelle in drug delivery, appears a promising novel material for drug delivery.
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Recent progress in multifunctional conjugated polymer nanomaterial-based synergistic combination phototherapy for microbial infection theranostics
TL;DR: In this paper , the authors provide an in-depth summary of the recent progress in multifunctional conjugated polymer-based nanomaterials for photo-based diagnostic and therapeutic applications to treat infections caused by multi-drug resistant pathogens.
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A 3D bioprinted decellularized extracellular matrix/gelatin/quaternized chitosan scaffold assembling with poly(ionic liquid)s for skin tissue engineering.
Jie Xu,Huan Fang,Yanli Su,Yue Kang,De Xu,Yung-Chi Cheng,Yi Nie,Hong Wang,Tianqing Liu,Kedong Song +9 more
TL;DR: In this paper , a tissue-specific extracellular matrix-based bioink, and dECM/Gel/QCS (dGQ) 3D scaffold assembling with poly(ionic liquid)s (PILs) was obtained by an extrusion 3D bioprinting technology and dynamic hydrogen bonding method.
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Injectable Dual‐Dynamic‐Bond Cross‐Linked Hydrogel for Highly Efficient Infected Diabetic Wound Healing
Shasha Yao,Yue Mei Zhao,Yifei Xu,Biao Jin,Monian Wang,Congcong Yu,Zhengxiao Guo,Shengnan Jiang,R. Tang,Xiangqian Fang,Shunwu Fan +10 more
TL;DR: A new type of healing hydrogel is developed that is based on histidine, a natural dietary essential amino acid that is significant for tissue formation that significantly promotes the healing of infected diabetic wounds in vivo and uniquely allows a full repair of wounds within ≈13 days, while ≈27 days are required for the healing process of the control group.
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Development of dual crosslinked mumio-based hydrogel dressing for wound healing application: Physico-chemistry and antimicrobial activity
Oyunchimeg Zandraa,Fahanwi Asabuwa Ngwabebhoh,Rahul Patwa,Hau Trung Nguyen,Marjan Motiei,Nabanita Saha,Tomas Saha,Petr Saha +7 more
TL;DR: In this paper, an antimicrobial mumio-based hydrogel dressing was developed for wound healing application, which achieved gel formation via a double crosslink network formation between gelatin (GT) and polyvinyl alcohol (PVA) using polyethylene glycol diglycidyl ether (PEGDE) and borax as crosslinking agents.
References
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Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
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Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.