Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
Reads0
Chats0
TLDR
In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
Citations
More filters
Journal ArticleDOI
Oromucosal precursors of in loco hydrogels for wound-dressing and drug delivery in oral mucositis: Retain, resist, and release.
TL;DR: Regrading critical factors, Carbopol® increased films' elasticity and flexibility, mucoadhesion, and the strength of the hydrogels, while higher concentrations led to thicker, more opaque, and lower strain resistance products.
Journal ArticleDOI
N‐dodecylated chitosan/graphene oxide composite cryogel for hemostasis and antibacterial treatment
Yixuan Qiu,Yanliang Dong,Yanliang Dong,Shuyue Zhao,Jianhua Zhang,Pingsheng Huang,Weiwei Wang,Anjie Dong,Liandong Deng +8 more
Book ChapterDOI
Self-healing polymers for composite structural applications
TL;DR: In this paper, the design and generic principles of self-healing polymers with different approaches are discussed and evaluated in different applications such as coating, aerospace, conductive device, and biological and pharmaceutical applications.
Journal ArticleDOI
Polyanionic self-healing hydrogels for the controlled release of cisplatin
TL;DR: In this article, a self-healing hydrogel containing phenylboronic acid (PBA) and phosphonic acid groups was prepared via a one-step Kabachnik-Fields (KF) reaction and free radical polymerization followed by an effective hydrolysis reaction.
Journal ArticleDOI
A Composite Hydrogel Containing Mesoporous Silica Nanoparticles Loaded With Artemisia argyi Extract for Improving Chronic Wound Healing
L. Xue,Tewei Deng,Rui Guo,Lu Peng,Junjun Guo,Fang Tang,Jin-Ding Lin,Sufang Jiang,Huijuan Lu,Xu-shun Liu,Lili Deng +10 more
TL;DR: In vivo wound healing of rat full-thickness cutaneous wounds demonstrated that the prepared GelMA/HAMA/MSN@AE hydrogel could significantly promote chronic wound healing by upregulating the expression of IL-4, TGF-β1, CD31, and α-SMA but downregulatingThe expression of TNF-α and IFN-γ and promoting M1-M2 macrophages polarization.
References
More filters
Journal ArticleDOI
Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
Journal ArticleDOI
Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
Journal ArticleDOI
Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
Journal ArticleDOI
Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Journal ArticleDOI
Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.