Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
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TLDR
In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
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Secretory Fluid-Aggregated Janus Electrospun Short Fiber Scaffold for Wound Healing.
Shutong Qian,Juan Wang,Zhimo Liu,Jiayi Mao,Binfan Zhao,Xiyuan Mao,Liucheng Zhang,Liying Cheng,Yuguang Zhang,Xiaoming Sun,Wenguo Cui +10 more
TL;DR: In vivo experiments show that this unique biometric Janus electrospun short fiber scaffold can trigger cascade release of curcumin by aggregating wound exudate, so as to accelerate wound healing process and promote collagen deposition and vascularization.
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Reactive-oxygen-species-scavenging nanomaterials for resolving inflammation.
TL;DR: In this article, the authors reviewed recent progress in research on nanotherapy based on reactive oxygen species (ROS) scavenging and discussed the underlying mechanisms of the employed nanomaterials.
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An M2 macrophage-polarized anti-inflammatory hydrogel combined with mild heat stimulation for regulating chronic inflammation and impaired angiogenesis of diabetic wounds
TL;DR: In this article , an M2 macrophage-polarized anti-inflammatory hydrogel (HTHE-M@D) combined with mild heat stimulation is designed for diabetic foot ulcers treatment.
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Flexible conducting polymer-based cellulose substrates for on-skin applications
TL;DR: The results suggested that the PEDOT-cellulose substrates could potentially be a better choice of smart skin dressings, integration interface between skin and artificial devices or implantable electronic materials.
References
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Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
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Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.