Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
Reads0
Chats0
TLDR
In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
Citations
More filters
Journal ArticleDOI
Controlled release of baricitinib from a thermos-responsive hydrogel system inhibits inflammation by suppressing JAK2/STAT3 pathway in acute spinal cord injury.
Xuan-Qi Zheng,Jin-Feng Huang,Jia-Liang Lin,Ya-Xin Zhu,Minqi Wang,Mei-Liang Guo,Xingjie Zan,Xingjie Zan,Ai-Min Wu +8 more
TL;DR: In this paper, the authors designed an injectable PLGA-PEG-PLGA thermos-sensitive hydrogel with baricitinib (Bari-P hydrogels) and measured its efficacy, physical and biological properties in vitro.
Journal ArticleDOI
Hydrogel adhesives for generalized wound treatment: Design and applications
TL;DR: In this article , a review comprehensively discusses the design and application of hydrogel adhesives on generalized wounds for wound closure and wound healing and the unique needs of various wounds for hydrogels.
Journal ArticleDOI
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress
Ke Xu,Ke Xu,Bo Chai,Kailun Zhang,Jun Xiong,Yiru Zhu,Jingyu Xu,Ningchen An,Weidong Xia,Hao Ji,Yanqing Wu,Hao Li,Jian Xiao,Feng Zhiguo,Hongyu Zhang +14 more
TL;DR: FGF10-PLGA microspheres accelerate wound healing presumably through modulating ER stress, indicating that the repair and functional reconstruction of skin defects needs to be solved urgently.
Journal ArticleDOI
Preparation and characterization of vancomycin-loaded chitosan/PVA/PEG hydrogels for wound dressing
Journal ArticleDOI
Manufacture of pH- and HAase-responsive hydrogels with on-demand and continuous antibacterial activity for full-thickness wound healing.
TL;DR: The hydrogels showed a pH- and HAase- dependent degradability, which allowed them to release more SS at infected wound and then exert on-demand and sustained antibacterial effect against S. aureus and E. coli.
References
More filters
Journal ArticleDOI
Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
Journal ArticleDOI
Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
Journal ArticleDOI
Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
Journal ArticleDOI
Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Journal ArticleDOI
Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.