Journal ArticleDOI
Antioxidant and Anti-malarial Properties of Catechins
Iwan Budiman,Rita Tjokropranoto,Wahyu Widowati,Fanny Rahardja,Maesaroh Maesaroh,Nurul Fauziah +5 more
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TLDR
This research was performed to evaluate the antioxidant and anti malarial activities of various catechins including catechin (C), epicatechin (EC), cateschine-gallate (CG), gallocatechingallate (GCG), epigallocatechin (EGC), Epicatechin-Gallate (ECG, epig allocatechin gallate (EGCG).Abstract:
Aims: This research was performed to evaluate the antioxidant and anti malarial activities of various catechins including catechin (C), epicatechin (EC), catechin-gallate (CG), gallocatechingallate (GCG), epigallocatechin (EGC), epicatechin-gallate (ECG), epigallocatechin gallate (EGCG). Study Design: The antioxidant activity was measured by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging activity and anti-malarial activity was determined by In vitro assay against P. falciparum culture, antioxidant activity was analyzed using linear regression analysis, and was continued by determining Inhibitory Concentration 50 (IC 50 ). The anti-malarial activity was analyzed by probit analysis and IC 50 determination.read more
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Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies.
Oluwole Solomon Oladeji,Abimbola Peter Oluyori,Deborah Temitope Bankole,Tokunbo Yemisi Afolabi +3 more
TL;DR: The study appraised the commonly used antimalarial plants in the study areas as they could lead to novel natural products for effective malaria therapy and commitment to scientifically explore the bioactive compounds, antimalaria potential and toxicological profile of these plants is inevitable.
Journal ArticleDOI
Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents.
TL;DR: This review aims to examine the most promising antiplasmodial phenolic compounds and derivatives isolated over the course of the last 28 years and discuss their structure-activity relationships, mechanisms of action, toxicity, new perspectives they could add to the fight against malaria, and the difficulties of transforming these potential compounds into new antimalarials.
Journal ArticleDOI
First ethnobotanical inventory and phytochemical analysis of plant species used by indigenous people living in the Maromizaha forest, Madagascar.
Isidoro Riondato,Dario Donno,Alessandro Roman,Vahinalahaja Eliane Razafintsalama,Thomas Petit,Maria Gabriella Mellano,Valeria Torti,Marta De Biaggi,Ernest Naivonirina Rakotoniaina,Cristina Giacoma,Gabriele Loris Beccaro +10 more
TL;DR: Investigating the potential medicinal properties of the plant species used by indigenous people in Maromizaha forest and providing the first ethnobotanical inventory of the area confirmed the importance of investigating the traditional use of plant species, suggesting the crucial role of ethnOBotanical studies for rural development, biodiversity conservation, and the sustainable use of plants in the studied area.
Journal ArticleDOI
Antioxidant Potential of Black, Green and Oolong Tea Methanol Extracts
Wahyu Widowati,Tati Herlina,Hana Ratnawati,Gabriella Constantia,I Dewa Gde Sathya Deva,Maesaroh Maesaroh +5 more
TL;DR: In this article, the authors evaluate phytochemical content, total phenolic content of black tea, green tea, and oolong tea extracts using catechin, quercetin, kaempferol, myricetin as standard.
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Antimalarial potentials of Stemonocoleus micranthus Harms (leguminoseae) stem bark in Plasmodium berghei infected mice.
TL;DR: The results of this study may have provided support on traditional therapeutic use of the plant in treatment of malaria by exhibiting antioxidant potentials which could have contributed individually or synergistically to antimalarial activities reported in this study.
References
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Journal ArticleDOI
Antioxidant Determinations by the Use of a Stable Free Radical
TL;DR: In this paper, the chemical nature of the antioxidant is known and a test specific for the compound or group of interest; for example, the nitroprusside test for sulphydryl groups.
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Green tea composition, consumption, and polyphenol chemistry.
TL;DR: In addition to the normal complement of plant cell enzymes, tea leaf contains an active polyphenol oxidase which catalyzes the aerobic oxidation of the catechins when the leaf cell structure is disrupted during black tea manufacture as mentioned in this paper.
Journal ArticleDOI
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
Jane V. Higdon,Balz Frei +1 more
TL;DR: The effects of tea and green tea catechins on biomarker of oxidative stress, especially oxidative DNA damage, appear very promising in animal models, but data on biomarkers of in vivo oxidative stress in humans are limited.
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Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies
Balz Frei,Jane V. Higdon +1 more
TL;DR: Most promising are the consistent findings in animal models of skin, lung, colon, liver and pancreatic cancer that tea and tea polyphenol administration inhibit carcinogen-induced increases in the oxidized DNA base, 8-hydroxy-2'-deoxyguanosine.
Journal ArticleDOI
Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals
TL;DR: It is recommended that antioxidant capacity be expressed as vitamin C mg/100 g equivalent (VCEAC) using the ABTS assay, which can be used in both organic and aqueous solvent systems, employs a specific absorbance at a wavelength remote from the visible region, and requires a short reaction time.