Applications of arterial spin labeled MRI in the brain.
TLDR
This review covers selected research and clinical applications of ASL MRI in the brain to illustrate its potential in both neuroscienceResearch and clinical care.Abstract:
Perfusion provides oxygen and nutrients to tissues and is closely tied to tissue function, and disorders of perfusion are major sources of medical morbidity and mortality. It has been almost two decades since the use of arterial spin labeling (ASL) for noninvasive perfusion imaging was first reported. While initial ASL MRI studies focused primarily on technological development and validation, a number of robust ASL implementations have emerged, and ASL MRI is now also available commercially on several platforms. As a result, basic science and clinical applications of ASL MRI have begun to proliferate. Although ASL MRI can be carried out in any organ, most studies to date have focused on the brain. This review covers selected research and clinical applications of ASL MRI in the brain to illustrate is potential in both neuroscience research and clinical care.read more
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Journal ArticleDOI
Recommended Implementation of Arterial Spin Labeled Perfusion MRI for Clinical Applications: A consensus of the ISMRM Perfusion Study Group and the European Consortium for ASL in Dementia
David C. Alsop,John A. Detre,Xavier Golay,Matthias Günther,Jeroen Hendrikse,Luis Hernandez-Garcia,Hanzhang Lu,Bradley J. MacIntosh,Bradley J. MacIntosh,Laura M. Parkes,Marion Smits,Matthias J.P. van Osch,Danny J.J. Wang,Eric C. Wong,Greg Zaharchuk +14 more
TL;DR: This review provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications and describes the major considerations and trade‐offs in implementing an ASL protocol and provides specific recommendations for a standard approach.
Journal ArticleDOI
Nature experience reduces rumination and subgenual prefrontal cortex activation
Gregory N. Bratman,J. Paul Hamilton,Kevin S Hahn,Gretchen C. Daily,Gretchen C. Daily,James J. Gross +5 more
TL;DR: A pathway by which nature experience may improve mental well-being is revealed and it is suggested that accessible natural areas within urban contexts may be a critical resource for mental health in the authors' rapidly urbanizing world.
Book ChapterDOI
Circadian Rhythms, Sleep Deprivation, and Human Performance
TL;DR: A key goal of this work is to identify biomarkers that accurately predict human performance in situations in which the circadian and sleep homeostatic systems are perturbed.
Journal ArticleDOI
A neuroradiologist’s guide to arterial spin labeling MRI in clinical practice
Madeline Grade,J. A Hernandez Tamames,J. A Hernandez Tamames,Francesca B. Pizzini,Eric Achten,Xavier Golay,Marion Smits +6 more
TL;DR: This review provides a practical guide and overview of the clinical applications of ASL of the brain, as well its potential pitfalls, and studies on ASL in brain tumour imaging indicate a high correlation between areas of increased CBF as measured with ASL and increased cerebral blood volume as measured by dynamic susceptibility contrast-enhanced perfusion imaging.
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Assessing pain objectively: the use of physiological markers
TL;DR: The most important developments in the field of objective markers of nociception or pain are introduced and shortcomings are highlighted to allow the reader to make informed decisions about what trends to watch in the future.
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