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Open AccessJournal ArticleDOI

Arsenic in the human food chain, biotransformation and toxicology- review focusing on seafood arsenic

Marianne Molin, +3 more
- 01 Jul 2015 - 
- Vol. 31, pp 249-259
TLDR
Recent findings indicate that the pre-systematic metabolism by colon microbiota play an important role for human metabolism of arsenicals, and new insight indicates that bioconversion of arsenosugars and arsenolipids in seafood results in urinary excretion of DMA, possibly also producing reactive trivalent arsenic intermediates.
About: 
This article is published in Journal of Trace Elements in Medicine and Biology.The article was published on 2015-07-01 and is currently open access. It has received 178 citations till now. The article focuses on the topics: Arsenobetaine & Arsenic.

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Citations
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Journal ArticleDOI

Algae as nutritional and functional food sources: revisiting our understanding

Mark L. Wells, +8 more
- 01 Apr 2017 - 
TL;DR: This work highlights this rapidly advancing area of algal science with a particular focus on the key research required to assess better the health benefits of an alga or algal product.
Journal ArticleDOI

Human exposure to organic arsenic species from seafood.

Vivien F. Taylor, +7 more
- 15 Feb 2017 - 
TL;DR: The extensive consumption of seafood globally, along with the preliminary toxicological profiles of these compounds and their confounding effect on assessing exposure to inorganic As, suggests further investigations and process-level studies on organic As are needed to fill the current gaps in knowledge.
Journal ArticleDOI

Arsenic and Environmental Health: State of the Science and Future Research Opportunities

Danielle J Carlin, +12 more
- 20 Nov 2015 - 
TL;DR: A review of emerging issues and research needs to address the multi-faceted challenges related to arsenic and environmental health and suggests integration of omics data with mechanistic and epidemiological data is a key step toward the goal of linking biomarkers of exposure and susceptibility to disease mechanisms and outcomes.
Journal ArticleDOI

Arsenic toxicity: Molecular targets and therapeutic agents

Valeria Marina Nurchi, +5 more
TL;DR: Primary prevention by reducing exposure of the millions of people exposed to unacceptable As levels should be the prioritized strategy and chelation treatment with therapeutic dithiols, in particular DMPS appears promising as regards alleviation of symptoms.
Journal ArticleDOI

Biochar versus bone char for a sustainable inorganic arsenic mitigation in water: what needs to be done in future research?

Susan S.A. Alkurdi, +5 more
- 22 Mar 2019 - 
TL;DR: This critical review attempts to provide a comprehensive overview for the first time on the potential of bio- and bone-char in the immobilization of inorganic As in water to offer a rational assessment of what is existing and what needs to be done in future research as an implication for As toxicity of human health risks.
References
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Journal ArticleDOI

Fish Intake, Contaminants, and Human Health: Evaluating the Risks and the Benefits

Dariush Mozaffarian, +1 more
- 18 Oct 2006 - 
TL;DR: For major health outcomes among adults, the benefits of fish intake exceed the potential risks, and for women of childbearing age, benefits of modest fish intake, excepting a few selected species, also outweigh risks.
Journal ArticleDOI

Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events.

Dariush Mozaffarian, +2 more
- 08 Nov 2011 - 
TL;DR: Overall, current data provide strong concordant evidence that n-3 PUFA are bioactive compounds that reduce risk of cardiac death.
Journal ArticleDOI

Arsenic Exposure and Toxicology: A Historical Perspective

Michael F. Hughes, +4 more
- 01 Oct 2011 - 
TL;DR: The mode of action of arsenic for its disease endpoints is currently under study, and two key areas are the interaction of trivalent arsenicals with sulfur in proteins and the ability of arsenic to generate oxidative stress.
ReportDOI

Toxicological profile for arsenic

C.-H. Selene J. Chou, +1 more
Journal ArticleDOI

A review of human carcinogens—Part C: metals, arsenic, dusts, and fibres

Kurt Straif, +10 more
- 01 May 2009 - 
TL;DR: Overall, the Working Group classifi ed arsenic and inorganic arsenic compounds as “carcinogenic to humans” (Group 1) and the organic arsenicals monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) are “not classifi able’ (Group 3).
Related Papers (5)

Human exposure to organic arsenic species from seafood.

Vivien F. Taylor, +7 more
- 15 Feb 2017 - 

Arsenic speciation in the environment

William R. Cullen, +1 more
- 01 Jun 1989 - 

Arsenic Exposure and Toxicology: A Historical Perspective

Michael F. Hughes, +4 more
- 01 Oct 2011 - 

Acute and chronic arsenic toxicity

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A review of the source, behaviour and distribution of arsenic in natural waters

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Frequently Asked Questions (1)
Q1. What are the future works in "Nutrition review arsenic in the human food chain, biotransformation and toxicology- review focusing on seafood arsenic" ?

As the main arsenical present in seafood, it is of great importance for future studies to clarify whether AB can be formed de novo as well as identifying its sources in humans.