Arterial cardiovascular events, statins, low-dose aspirin and subsequent risk of venous thromboembolism: a population-based case-control study.
Henrik Toft Sørensen,Erzsébet Horváth-Puhó,Kirstine Kobberøe Søgaard,Steffen Christensen,Søren Paaske Johnsen,Reimar W. Thomsen,Paolo Prandoni,John A. Baron +7 more
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TLDR
Patients with cardiovascular events are at a short‐term increased risk of venous thromboembolism, as the study is non‐randomized residual confounding cannot be excluded.About:
This article is published in Journal of Thrombosis and Haemostasis.The article was published on 2009-04-01 and is currently open access. It has received 168 citations till now. The article focuses on the topics: Relative risk & Stroke.read more
Citations
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Prevention of VTE in Nonsurgical Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Yngve Falck-Ytter,Charles W. Francis,Norman A. Johanson,Catherine Curley,Ola E. Dahl,Sam Schulman,Thomas L. Ortel,Stephen G. Pauker,Clifford W. Colwell +8 more
TL;DR: In this article, the authors focus on optimal prophylaxis to reduce postoperative pulmonary embolism and DVT following major orthopedic surgery, and suggest the use of low-molecular-weight heparin in preference to the other agents we have recommended as alternatives.
Journal ArticleDOI
A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism
Robert J. Glynn,Eleanor Danielson,Francisco Antonio Helfenstein Fonseca,Jacques Genest,Antonio M. Gotto,John J.P. Kastelein,Wolfgang Koenig,Peter Libby,Alberto J. Lorenzatti,Jean G. MacFadyen,Børge G. Nordestgaard,James Shepherd,James T. Willerson,Paul M. Ridker +13 more
TL;DR: In a randomized trial of 17,802 apparently healthy men and women with both low-density lipoprotein (LDL) cholesterol levels of less than 130 mg per deciliter (34 mmol per liter) and high-sensitivity C-reactive protein levels of 20 mg per liter or higher to receive rosuvastatin or placebo.
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Aspirin for Preventing the Recurrence of Venous Thromboembolism
Cecilia Becattini,Giancarlo Agnelli,Alessandro Schenone,Sabine Eichinger,Eugenio Bucherini,Mauro Silingardi,Marina Bianchi,Marco Moia,Walter Ageno,Maria Rita Vandelli,Elvira Grandone,Paolo Prandoni +11 more
TL;DR: Aspirin reduced the risk of recurrence when given to patients with unprovoked venous thromboembolism who had discontinued anticoagulant treatment, with no apparent increase in therisk of major bleeding.
Journal ArticleDOI
Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer
Patrizia Gazzerro,Maria Proto,Giuseppina Gangemi,Anna Maria Malfitano,Elena Ciaglia,Simona Pisanti,Antonietta Santoro,Chiara Laezza,Maurizio Bifulco +8 more
TL;DR: The pharmacology of the statins is reviewed, providing a comprehensive update of the current knowledge of their effects on tissues, biological processes, and pathological conditions, and the disappointing evidence on the possible future use of statin-based drugs in cancer therapy is dissected.
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New insights into the mechanisms of venous thrombosis.
TL;DR: The most common site for initiation of the thrombus appears to be the valve pocket sinus, due to its tendency to become hypoxic.
References
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Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
TL;DR: Aspirin (or another oral antiplatelet drug) is protective in most types of patient at increased risk of occlusive vascular events, including those with an acute myocardial infarction or ischaemic stroke, unstable or stable angina, previous myocardian infarctions, stroke or cerebral ischaemia, peripheral arterial disease, or atrial fibrillation.
Journal ArticleDOI
Cardiovascular risk factors and venous thromboembolism: a meta-analysis.
TL;DR: Cardiovascular risk factors are associated with venous thromboembolism and this association is clinically relevant with respect to individual screening, risk factor modification, and primary and secondary prevention of VTE.
Journal ArticleDOI
Epidemiology. When an entire country is a cohort.
TL;DR: Denmark has gathered more data on its citizens than any other country, and scientists are pushing to make this vast array of statistics even more useful by easing restrictions on the use of data coded by personal identification numbers.
Journal ArticleDOI
Postmenopausal Hormone Therapy Increases Risk for Venous Thromboembolic Disease: The Heart and Estrogen/progestin Replacement Study
Deborah Grady,Nanette K. Wenger,David M. Herrington,Steven S. Khan,Curt D. Furberg,Donald B. Hunninghake,Eric Vittinghoff,Stephen B. Hulley +7 more
TL;DR: The Heart and Estrogen/progestin Replacement Study was a randomized, blinded, placebo-controlled trial of the effect of daily conjugated equine estrogen on the rate of new coronary events in postmenopausal women with established coronary heart disease, and one of the specified secondary outcomes of this trial was venous thromboembolism.
Journal ArticleDOI
An association between atherosclerosis and venous thrombosis.
Paolo Prandoni,Franca Bilora,Antonio Marchiori,Enrico Bernardi,F. Petrobelli,Anthonie W. A. Lensing,Martin H. Prins,Antonio Girolami +7 more
TL;DR: There is an association between atherosclerotic disease and spontaneous venous thrombosis and the strength of this association did not change in a multivariate analysis that accounted for risk factors for atherosclerosis.