Journal ArticleDOI
Attention-deficit/hyperactivity disorder in adults: an overview
Stephen V. Faraone,Joseph Biederman,Thomas J. Spencer,Timothy E. Wilens,Larry J. Seidman,Larry J. Seidman,Eric Mick,Alysa E. Doyle +7 more
TLDR
Assessment of clinical, family, psychopharmacologic, neurobiological, and outcome studies found multiple reports describing adults with clinical features highly reminiscent of the childhood ADHD, suggesting converging lines of evidence support the validity of ADHD in adults.About:
This article is published in Biological Psychiatry.The article was published on 2000-07-01. It has received 650 citations till now. The article focuses on the topics: Attention deficit hyperactivity disorder & Developmental disorder.read more
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Attention deficit/hyperactivity disorder as a right hemisphere syndrome. Selective literature review and detailed neuropsychological case studies.
TL;DR: It is suggested that the pleomorphic presentations of ADHD can be understood in terms of a spectrum of disturbances in overlapping neural regions, especially involving frontal and parietal areas of the right hemisphere and their connections to subcortical structures (including the striatum, limbic system and diencephalic nuclei).
Journal ArticleDOI
A cognitive neuropsychological model of antidepressant drug action
TL;DR: It is argued that primary mode of action of antidepressant drugs may be to remediate negative biases in information processing providing a more positive social environment in which the patient can relearn emotional associations fostering later improvement in mood.
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Animal models concerning the role of dopamine in attention-deficit hyperactivity disorder.
TL;DR: The evaluation of rodent models of ADHD particularly with respect to dopaminergic systems is attempted and it is concluded that the neonatal 6-hydroxy-dopamine lesioned rat and DA transporter knockout/knockdown mice have the highest degree of validity for ADHD.
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Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder
Vlad Kustanovich,Barry Merriman,James J. McGough,James T. McCracken,Susan L. Smalley,Stan F. Nelson +5 more
TL;DR: A trend is found consistent with biased transmission of the TC haplotype of SNAP-25 in all transmissions and a significant distortion is detected when paternal transmissions were evaluated.
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In search of predictive endophenotypes in addiction: insights from preclinical research
TL;DR: The principal findings emanating from preclinical animal research on addiction are surveyed and discussed to highlight how specific behavioral endophenotypes of presumed genetic origin differentially contribute to compulsive forms of drug seeking and taking and, in particular, how these differentiate between different classes of stimulant and non‐stimulant drugs of abuse.
References
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Book
Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment
TL;DR: Barkley et al. as discussed by the authors discussed the nature of ADHD, primary symptoms, diagnosis criteria, prevalence, and gender differences, and the treatment of ADHD in adults.
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Executive Functions and Developmental Psychopathology
TL;DR: It is revealed that EF deficits are consistently found in both ADHD and autism but not in CD (without ADHD) or in TS, and both the severity and profile of EF deficits appears to differ across ADHD and Autism.
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Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia
Eli Robins,Samuel B. Guze +1 more
TL;DR: It was shown by follow-up and family studies that poor prognosis cases can be validly separated clinically from good prediction cases, and the authors conclude that good prognosis "schizophrenia" is not mild schizophrenia, but a different illness.
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Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders.
TL;DR: The literature supports considerable comorbidity of attention deficit hyperactivity disorder with conduct disorder, oppositional defiant disorder, mood disorders, anxiety disorders, learning disabilities, and other disorders, such as mental retardation, Tourette's syndrome, and borderline personality disorder.
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Externalizing behavior problems and academic underachievement in childhood and adolescence: causal relationships and underlying mechanisms.
TL;DR: In this paper, the authors reviewed concepts and measurement issues surrounding externalizing behavior problems and academic underachievement, the strength and specificity of the covariation between these domains, and the viability of explanatory models that link these areas.