Journal ArticleDOI
Attention-deficit/hyperactivity disorder in adults: an overview
Stephen V. Faraone,Joseph Biederman,Thomas J. Spencer,Timothy E. Wilens,Larry J. Seidman,Larry J. Seidman,Eric Mick,Alysa E. Doyle +7 more
TLDR
Assessment of clinical, family, psychopharmacologic, neurobiological, and outcome studies found multiple reports describing adults with clinical features highly reminiscent of the childhood ADHD, suggesting converging lines of evidence support the validity of ADHD in adults.About:
This article is published in Biological Psychiatry.The article was published on 2000-07-01. It has received 650 citations till now. The article focuses on the topics: Attention deficit hyperactivity disorder & Developmental disorder.read more
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Journal ArticleDOI
Molecular Genetics of Attention-Deficit/Hyperactivity Disorder
Stephen V. Faraone,Roy H. Perlis,Alysa E. Doyle,Jordan W. Smoller,Jennifer J. Goralnick,Meredith A. Holmgren,Pamela Sklar +6 more
TL;DR: Family, twin, and adoption studies provide compelling evidence that genes play a strong role in mediating susceptibility to ADHD, and seven genes for which the same variant has been studied in three or more case-control or family-based studies show statistically significant evidence of association with ADHD.
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Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in children.
Joseph Biederman,Michael C. Monuteaux,Alysa E. Doyle,Larry J. Seidman,Timothy E. Wilens,Frances Ferrero,Christie L. Morgan,Stephen V. Faraone +7 more
TL;DR: The association between executive function deficits (EFDs) and functional outcomes were examined among children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and these results support screening children with ADHD for EFDs to prevent academic failure.
Journal ArticleDOI
Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder
TL;DR: Findings indicate that overall cognitive ability is significantly lower among persons with ADHD and that FSIQ may show as large a difference between ADHD and control participants as most other measures.
Journal ArticleDOI
Structural brain imaging of attention-deficit/hyperactivity disorder.
TL;DR: The results suggest that the brain is altered in a more widespread manner than has been previously hypothesized, and developmental studies are needed to address the evolution of this brain disorder into adulthood.
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Neurocognitive Effects of Methamphetamine: A Critical Review and Meta-analysis
J. Cobb Scott,Steven Paul Woods,Steven Paul Woods,Georg E. Matt,Rachel Meyer,Robert K. Heaton,J. Hampton Atkinson,Igor Grant +7 more
TL;DR: A meta-analysis of the neuropsychological effects of MA abuse/dependence revealed broadly medium effect sizes, showing deficits in episodic memory, executive functions, information processing speed, motor skills, language, and visuoconstructional abilities.
References
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A systematic assessment of tricyclic antidepressants in the treatment of adult attention-deficit hyperactivity disorder.
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Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder.
TL;DR: The take-home message was that untreated ADHD was a significant risk factor for SUD in adolescence, but pharmacotherapy was associated with a significantly reduced risk.
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Controlled trial of high doses of pemoline for adults with attention-deficit/hyperactivity disorder
Timothy E. Wilens,Joseph Biederman,Thomas J. Spencer,Jean A. Frazier,Jefferson B. Prince,Jeff Q. Bostic,Michael Rater,Jennifer Soriano,Mary Hatch,Melissa Sienna,Rachael B. Millstein,Ana M. Abrantes +11 more
TL;DR: Results indicate that pemoline is moderately effective in the treatment of ADHD in adults, and given the limited efficacy, tolerability, and concerns of hepatic dysfunction, it should be considered as second-line medication for treating ADHD in adult.
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History of childhood hyperactivity in a clinic population of opiate addicts.
TL;DR: Demographic and developmental features such as high male to female sex ratio, normal intelligence quotient but lower level of educational and occupational achievement, and earlier arrest record supported the retrospective diagnosis of childhood hyperactivity and suggested that those with a history of hyperactivity in childhood were manifesting adult sequelae of the disorder.