Journal ArticleDOI
Benzodiazepine gastrin and brain cholecystokinin receptor ligands; L-365,260
Mark G. Bock,Robert M. DiPardo,Ben E. Evans,Kenneth E. Rittle,Willie L. Whitter,Daniel F. Veber,Paul S. Anderson,Roger M. Freidinger +7 more
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This article is published in Journal of Medicinal Chemistry.The article was published on 1989-01-01. It has received 305 citations till now. The article focuses on the topics: Cholecystokinin receptor & Cholecystokinin B receptor.read more
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Peptidomimetics for Receptor Ligands—Discovery, Development, and Medical Perspectives
TL;DR: Peptidomimetics, compounds that act as substitutes for peptides in their interaction with receptors, have been synthesized and show higher metabolic stability, better bioavailability, and longer duration of action.
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Biological actions of cholecystokinin
TL;DR: New findings are presented on potent, nonpeptide CCK antagonists, selective for the two CCK receptor subtypes, which demonstrate that endogenous CCK has biologically important effects on physiology and behavior.
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The Current Status of Heterocyclic Combinatorial Libraries.
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Neuropeptides--an overview
Tomas Hökfelt,Christian Broberger,Zhi-Qing David Xu,Valeriy Sergeyev,Ruud Ubink,Margarita Diez +5 more
TL;DR: It seems that peptides may play a role particularly when the nervous system is stressed, challenged or afflicted by disease, and that peptidergic systems may, therefore, be targets for novel therapeutic strategies.