Journal ArticleDOI
Biomaterial and implant surfaces: on the role of cleanliness, contamination, and preparation procedures.
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TLDR
The surface status of implants is expected to be important for in vivo function, and should thus be controlled and standardized, and different preparation procedures such as conventional machining, plasma treatment, and sterilization are discussed.Abstract:
Material specificity in implant-tissue interactions derives primarily from the surface properties (chemical composition, microstructure, etc.) of the implant. This article addresses several questions related to implant and biomaterial surfaces: What is the status of real implant surfaces (composition, cleanliness, contamination, microstructure, etc.), and how does it vary with preparation procedures? Can the surface status be varied and analyzed in a controlled manner? How significant are surface status variations for in vivo function? And so on. We discuss clean surfaces, how they are contaminated, and how the contamination may affect the properties. We also discuss different preparation procedures, such as conventional machining, plasma treatment, and sterilization. Three important conclusions are drawn: (i) The surface status of a particular implant material may vary widely depending on its preparation and handling history. (ii) The surface status of implants is expected to be important for in vivo function, and should thus be controlled and standardized. (iii) It is usually not possible to predict how a change in surface status will affect the long-term, in vivo function of an implant.read more
Citations
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Surface modification of titanium, titanium alloys, and related materials for biomedical applications
TL;DR: A review of surface modification techniques for titanium and titanium alloys can be found in this article, where the authors have shown that the wear resistance, corrosion resistance, and biological properties can be improved selectively using the appropriate surface treatment techniques while the desirable bulk attributes of the materials are retained.
Journal ArticleDOI
Mediation of Biomaterial–Cell Interactions by Adsorbed Proteins: A Review
TL;DR: This review illustrates the mediation of cell responses to biomaterials by adsorbed proteins, in the context of osteoblasts and selected materials used in orthopedic implants and bone tissue engineering.
Journal ArticleDOI
High surface energy enhances cell response to titanium substrate microstructure.
Ge Zhao,Zvi Schwartz,Marco Wieland,Frank Rupp,Jürgen Geis-Gerstorfer,David L. Cochran,Barbara D. Boyan +6 more
TL;DR: Osteoblasts grown on modified Ti surfaces exhibited a more differentiated phenotype characterized by increased alkaline phosphatase activity and osteocalcin and generated an osteogenic microenvironment through higher production of PGE2 and TGF-beta1 and 1alpha,25OH2D3 increased these effects in a manner that was synergistic with high surface energy.
Journal ArticleDOI
Quartz crystal microbalance with dissipation monitoring of supported lipid bilayers on various substrates
TL;DR: A protocol for constructing zwitterionic SLBs supported on silicon oxide and titanium oxide, and a recently developed strategy that uses an amphipathic, α-helical (AH) peptide to form SLBs on gold and Titanium oxide substrates are presented.
Journal ArticleDOI
The relative influence of the topography and chemistry of TiAl6V4 surfaces on osteoblastic cell behaviour.
Karine Anselme,P. Linez,Maxence Bigerelle,D. Le Maguer,A. Le Maguer,Pierre Hardouin,Hartmut F. Hildebrand,Alain Iost,Jean-Marie Leroy +8 more
TL;DR: The findings show the significance of chemical surface analysis after any surface treatment of titanium-based implants before any biological use, and the suspicion that the concomittant effect of surface roughness amplitude and AlOx surface concentration has an effect on osteoblastic cell proliferation and adhesion.
References
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Journal ArticleDOI
The interface zone of inorganic implants in vivo: Titanium implants in bone.
Tomas Albrektsson,P-I. Brånemark,Hans-Arne Hansson,Bengt Herbert Kasemo,Kåre Larsson,Ingmar Lundström,Douglas H. McQueen,Richard Skalak +7 more
TL;DR: The interface zone between titanium implants and bone is considered at the macroscopic, microscopic, and molecular levels and includes a tightly adherent titanium oxide layer on the surface of the implant which may be similar to a ceramic material in relation to tissue response.
Journal ArticleDOI
Surface properties determine bioadhesive outcomes: Methods and results
TL;DR: Experimental evidence for the influence of different surface energy states on tissue incorporation of biomedical materials is developed and the advantages of proper surface treatment to favor the desired degree of biological adhesion are apparent.