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BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities.

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TLDR
The BIOPEP-UWM™ database of bioactive peptides has recently become a popular tool in the research on bio active peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases.
Abstract
The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.

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Molecular representations in AI-driven drug discovery: a review and practical guide

TL;DR: This review presents some of the most popular electronic molecular and macromolecular representations used in drug discovery, many of which are based on graph representations, and describes applications of these representations in AI-driven drug discovery.
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Plant protein-derived antioxidant peptides: Isolation, identification, mechanism of action and application in food systems: A review

TL;DR: This review provides a timely reference for the development of new antioxidant peptides in functional foods and nutritional supplements and recommends large-scale commercial production of plant protein-derived antioxidant peptide production.
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Current Trends of Bioactive Peptides-New Sources and Therapeutic Effect

TL;DR: This review will describe peptides inhibiting the development of current diseases, peptides with antimicrobial properties, and new alternative sources of peptides based on the current knowledge and documentation of their bioactivity.
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In vivo bioactivities of food protein-derived peptides – a current review

TL;DR: A current perspective on the production and main biological activities of peptides derived from food proteins is presented, allowing a rapid in silico screening of the bioactive potential of dietary proteins.
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Identification of New Peptides from Fermented Milk Showing Antioxidant Properties: Mechanism of Action.

TL;DR: Several antioxidant peptides extracted from fermented milk proteins were investigated and the potential ability of N-15-M, Q-14-R and A-17-E to bind Keap1 was confirmed, showing their destabilizing effect onKeap1/Nrf2 interaction.
References
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Open Babel: An open chemical toolbox

TL;DR: The implementation of Open Babel is detailed, key advances in the 2.3 release are described, and a variety of uses are outlined both in terms of software products and scientific research, including applications far beyond simple format interconversion.
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DrugBank 5.0: a major update to the DrugBank database for 2018

TL;DR: This year’s update, DrugBank 5.0, represents the most significant upgrade to the database in more than 10 years and significant improvements have been made to the quantity, quality and consistency of drug indications, drug binding data as well as drug-drug and drug-food interactions.
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SMILES, a chemical language and information system. 1. introduction to methodology and encoding rules

TL;DR: This chapter discusses the construction of Benzenoid and Coronoid Hydrocarbons through the stages of enumeration, classification, and topological properties in a number of computers used for this purpose.
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ZINC 15 – Ligand Discovery for Everyone

TL;DR: A suite of ligand annotation, purchasability, target, and biology association tools, incorporated into ZINC and meant for investigators who are not computer specialists, offer new analysis tools that are easy for nonspecialists yet with few limitations for experts.
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