Journal ArticleDOI
Can lifestyle changes reverse coronary heart disease?: The Lifestyle Heart Trial
Dean Ornish,S. E. Brown,James H. Billings,Larry Scherwitz,William T. Armstrong,Thomas A. Ports,Sandra McLanahan,Richard L. Kirkeeide,K L Gould,Richard J. Brand +9 more
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TLDR
Comprehensive lifestyle changes may be able to bring about regression of even severe coronary atherosclerosis after only 1 year, without use of lipid-lowering drugs.About:
This article is published in The Lancet.The article was published on 1990-07-21. It has received 2010 citations till now. The article focuses on the topics: Coronary atherosclerosis.read more
Citations
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Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
Journal ArticleDOI
The pathogenesis of coronary artery disease and the acute coronary syndromes (1).
TL;DR: The two hypotheses to explain the pathogenesis of atherosclerosis, the "incrustation" hypothesis and the "lipid" hypothesis, are now known.
Journal ArticleDOI
Coronary heart disease: seven dietary factors.
T.L.V. Ulbricht,D.A.T. Southgate +1 more
TL;DR: The polyunsaturated/saturated ratio as a measure of the propensity of the diet to influence the incidence of coronary heart disease should be replaced by indices of atherogenicity and thrombogenicity.
Journal ArticleDOI
Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials.
Rod S Taylor,Allan Brown,Shah Ebrahim,Judith Jolliffe,Hussein Noorani,Karen Rees,Becky Skidmore,James A. Stone,David R. Thompson,Neil Oldridge +9 more
TL;DR: A systematic review and meta-analysis of randomized controlled trials was conducted in this paper, showing that cardiac rehabilitation was associated with reduced all-cause mortality (odds ratio [OR] = 0.80; 95% confidence interval [CI]: 0.68 to 0.93).
Journal ArticleDOI
Health benefits of dietary fiber
James W. Anderson,Pat Baird,Richard H. Davis,Stefanie P. Ferreri,Mary Knudtson,Ashraf Koraym,Valerie Waters,Christine L. Williams +7 more
TL;DR: Dietary fiber intake benefits a number of gastrointestinal disorders including the following: gastroesophageal reflux disease, duodenal ulcer, diverticulitis, constipation, and hemorrhoids.
References
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Journal ArticleDOI
Beneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts
David H. Blankenhorn,Sharon Nessim,Ruth Johnson,Miguel E. Sanmarco,Stanley P. Azen,Linda Cashin-Hemphill +5 more
TL;DR: The Cholesterol-Lowering Atherosclerosis Study (CLAS) was a randomized, placebo-controlled, angiographic trial testing combined colestipol hydrochloride and niacin therapy in 162 nonsmoking men aged 40 to 59 years with previous coronary bypass surgery.
Journal ArticleDOI
Reducing the Health Consequences of Smoking: 25 Years of Progress. A Report of the Surgeon General.
Journal ArticleDOI
Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction.
TL;DR: NICOTINE has been consumed in the form of tobacco and other plants for many hundreds of years and has become available as a pharmaceutical agent, marketed as a chewing gum to help people stop smoking.
Journal ArticleDOI
Apoprotein composition of very low density lipoproteins of human serum.
TL;DR: In this paper, the tetramethylurea was used to delipidates the lipoprotein and selectively precipitates apolipoprotein B. The mean content of apoprotein B in 43 samples from normolipidemic and hyperlipemic subjects was 36.9(+/-1.2 SEM)% of total protein, the distribution of the major soluble apoproteins as mean (+/-SEM) percentage of the soluble fraction was : R-serine, 5.3+/-o.5; arginine-rich, 20.
Journal ArticleDOI
Trial of relaxation in reducing coronary risk: four year follow up.
TL;DR: The treatment group had group sessions of one hour a week for eight weeks in which they were taught breathing exercises, relaxation, and meditation and about managing stress, and after four years of follow up differences in blood pressure were maintained.
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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more