Journal ArticleDOI
Carbon catabolite repression in bacteria.
Jörg Stülke,Wolfgang Hillen +1 more
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TLDR
The mechanism of lactose-glucose diauxie in Escherichia coli has been reinvestigated and was found to be caused mainly by inducer exclusion, and the gene encoding HPr kinase, a key component of CCR in many bacteria, was discovered recently.About:
This article is published in Current Opinion in Microbiology.The article was published on 1999-04-01. It has received 471 citations till now. The article focuses on the topics: Catabolite repression & Fed-batch culture.read more
Citations
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Journal ArticleDOI
Carbon catabolite repression in bacteria: many ways to make the most out of nutrients
Boris Görke,Jörg Stülke +1 more
TL;DR: The most recent findings on the different mechanisms that have evolved to allow bacteria to use carbon sources in a hierarchical manner are discussed.
Journal ArticleDOI
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
Nader Sanai,Anthony D. Tramontin,Alfredo Quiñones-Hinojosa,Nicholas M. Barbaro,Nalin Gupta,Sandeep Kunwar,Michael T. Lawton,Michael W. McDermott,Andrew T. Parsa,José Manuel García Verdugo,Mitchel S. Berger,Arturo Alvarez-Buylla +11 more
TL;DR: A ribbon of SVZ astrocytes lining the lateral ventricles of the adult human brain that proliferate in vivo and behave as multipotent progenitor cells in vitro is described.
Journal ArticleDOI
How Phosphotransferase System-Related Protein Phosphorylation Regulates Carbohydrate Metabolism in Bacteria
TL;DR: The known protein phosphorylation-related regulatory functions of the PTS are summarized, which shows that the PTS regulation network not only controls carbohydrate uptake and metabolism but also interferes with the utilization of nitrogen and phosphorus and the virulence of certain pathogens.
Journal ArticleDOI
The acetate switch.
TL;DR: Evidence is presented that nucleoid proteins orchestrate a progression of distinct nucleoprotein complexes to ensure proper transcription of its gene and that acetyl∼P influences cellular processes from organelle biogenesis to cell cycle regulation and from biofilm development to pathogenesis.
Journal ArticleDOI
Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling
Brandon d. Moore,Li Zhou,Filip Rolland,Qi Hall,Wan-Hsing Cheng,Yanxia Liu,Ildoo Hwang,Tamara L. Jones,Jen Sheen +8 more
TL;DR: HXK1 mutants lacking catalytic activity still support various signaling functions in gene expression, cell proliferation, root and inflorescence growth, and leaf expansion and senescence, thus demonstrating the uncoupling of glucose signaling from glucose metabolism.
References
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Journal ArticleDOI
Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria.
TL;DR: The IIAGlc protein, part of the glucose-specific PTS, is a central regulatory protein which in its nonphosphorylated form can bind to and inhibit several non-PTS uptake systems and thus prevent entry of inducers.
Journal ArticleDOI
Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete
Claire M. Fraser,Steven J. Norris,George M. Weinstock,Owen White,Granger G. Sutton,Robert J. Dodson,Michelle L. Gwinn,Erin Hickey,Rebecca A. Clayton,Karen A. Ketchum,Erica Sodergren,John M. Hardham,Michael P. McLeod,Steven L. Salzberg,Jeremy Peterson,Hanif Khalak,Delwood Richardson,Jerrilyn K. Howell,Monjula Chidambaram,Teresa Utterback,Lisa McDonald,Patricia Artiach,Cheryl Bowman,Matthew D. Cotton,Claire Fujii,Stacey Garland,Bonnie Hatch,Kurt Horst,Kevin Roberts,Mina Sandusky,Janice Weidman,Hamilton O. Smith,J. Craig Venter +32 more
TL;DR: Comparison of the T. pallidum genome sequence with that of another pathogenic spirochete, Borrelia burgdorferi, the agent of Lyme disease, identified unique and common genes and substantiates the considerable diversity observed among pathogenicSpirochetes.
Journal ArticleDOI
Catabolite repression in Bacillus subtilis: a global regulatory mechanism for the gram-positive bacteria?
TL;DR: Three components involved in catabolite repression of gene expression in Bacillus have been identified and direct protein‐protein interaction between CcpA and HPr(Ser‐P) was recently demonstrated and constitutes a link between metabolic activity and CR.
Journal ArticleDOI
Catabolite repression and inducer control in Gram-positive bacteria
Milton H. Saier,Sylvie Chauvaux,Gregory M. Cook,Josef Deutscher,Ian T. Paulsen,Jonathan Reizer,Jing-Jing Ye +6 more
TL;DR: Results currently available clearly indicate that the metabolite-activated protein kinase-mediated phosphorylation of Ser-46 in HPr plays a key role in catabolite repression and the control of inducer levels in low-GC Gram-positive bacteria.
Journal ArticleDOI
PRD — a protein domain involved in PTS‐dependent induction and carbon catabolite repression of catabolic operons in bacteria
TL;DR: Several operon‐specific transcriptional regulators, including antiterminators and activators, contain a duplicated conserved domain, the PRD, which are functionally specialized in either induction or catabolite repression.
Related Papers (5)
Carbon catabolite repression in bacteria : choice of the carbon source and autoregulatory limitation of sugar utilization
Carbon catabolite repression in bacteria: many ways to make the most out of nutrients
Boris Görke,Jörg Stülke +1 more