Book ChapterDOI
Chemistry and Biological Activities of Isoprenylated Flavonoids from Medicinal Plants (Moraceous Plants and Glycyrrhiza Species)
TLDR
In this paper, the biological activities of the isoprenylated-flavonoids from the root barks and/or barks of moraceous plants and from Glycyrrhiza species were reviewed.Abstract:
Among a large number of phenolic compounds isolated from natural source, various isoprenoid-substituted phenolic compounds have often been found in plants. Moraceous plants and licorice ( Glycyrrhiza species) are rich sources of the isoprenoid-substituted phenolic compounds, including flavonoids. Some of the Morus flavonoids, such as kuwanons G and H, have been regarded as optically active Diels-Alder type adducts. Furthermore, some of the isoprenylated-flavonoids from the moraceous plants and licorice showed the interesting biological activities. This article reviews the biological activities of the isoprenylated-flavonoids from the root barks and/or barks of moraceous plants and from Glycyrrhiza species by our group. The chemical studies concerning the biological activities of these compounds are also described briefly.read more
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Journal ArticleDOI
Hypoglycemic effect of Egyptian Morus alba root bark extract : Effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats
TL;DR: The data obtained from this study revealed that MRBF-3 may protect pancreatic beta cells from degeneration and diminish lipid peroxidation, however, this is the first biological screening of the Egyptian Morus alba root bark; further future merit studies including clinical study will be necessary in order to confirm the results obtained.
Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestogens
Lund, T. , D.,West, T. , W.,Tian, L. , Y.,Bu, L. , H.,Simmons, D. , L.,Setchell, K. , D. R.,H. Adlercreutz,Lephart, E. , D. +7 more
TL;DR: Dietary phytoestrogens significantly sex-reversed the normal sexually dimorphic expression of VSM in rats, suggesting that dietary soy derived phy toestrogens can influence learning and memory and alter the expression of proteins involved in neural protection and inflammation in rats.
Journal ArticleDOI
Antinephritis and radical scavenging activity of prenylflavonoids
TL;DR: Antinephritis activity of 5 prenylflavonoids similar to glabridin, isolated from Morus alba, Artocarpus communis, Glycyrrhiza uralensis and G. inflata, was evaluated in mice with glomerular disease (Masugi-nephritis).
Journal ArticleDOI
Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata.
TL;DR: The structure of the new retrochalcone was elucidated through a spectroscopic analysis and cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin.
Journal ArticleDOI
Antimicrobial activity of 2-arylbenzofurans from Morus species against methicillin-resistant Staphylococcus aureus.
TL;DR: Nine 2-arylbenzofurans isolated from Morus species were tested for their antimicrobial activities against methicillin-sensitive Staphylococcus aureus, and chalcomoracin exhibited considerable antibacterial activity against MRSAs.
References
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Book
Progress in the Chemistry of Organic Natural Products
TL;DR: The chemistry and biology of Rocaglamides and related derivatives from Aglaia species (Meliacease) are discussed in detail in a recent paper by.
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Studies in natural products chemistry
TL;DR: The series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.