Journal ArticleDOI
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
Govind J. Kapadia,Magnus A. Azuine,Rajagopalan Sridhar,Yoko Okuda,Atsushi Tsuruta,Eiichiro Ichiishi,Teruo Mukainake,Midori Takasaki,Takao Konoshima,Hoyoku Nishino,Harukuni Tokuda +10 more
TLDR
Findings suggest that beetroot, which is a regularly consumed natural product colorant is an effective cancer chemopreventive agent in mice, and warrants more attention for possible human applications in the control of malignancy.About:
This article is published in Pharmacological Research.The article was published on 2003-02-01. It has received 162 citations till now. The article focuses on the topics: Betanin & Tumor initiation.read more
Citations
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Journal ArticleDOI
Betalains: properties, sources, applications, and stability ? a review.
TL;DR: This review synthesises the published literature on basic chemistry of betalains, their sources and chemical stability, and several works are mentioned which have demonstrated the potent antioxidant activity of bet alains, which has been associated with protection against degenerative diseases.
Journal ArticleDOI
The potential benefits of red beetroot supplementation in health and disease
TL;DR: Beetroot’s biological activity is discussed and evidence from studies that specifically investigated the effect of beetroot supplementation on inflammation, oxidative stress, cognition and endothelial function are evaluated.
Journal ArticleDOI
Antioxidant activity and phenolic content of betalain extracts from intact plants and hairy root cultures of the red beetroot Beta vulgaris cv. Detroit dark red.
TL;DR: The high antioxidant activity of the hairy root extracts was associated with increased concentrations (more than 20-fold) of total phenolic concomitant compounds, which may have synergistic effects with betalains.
Journal ArticleDOI
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate‐nitrite‐nitric oxide pathway
Satnam Lidder,Andrew J. Webb +1 more
TL;DR: The Nitrate 'Veg-Table' with 'Nitrate Units' is developed to achieve a nitrate intake that is likely to be sufficient to derive benefit, but also to minimize the risk of potential side effects from excessive ingestion, given the current available evidence.
References
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Journal ArticleDOI
Chemoprevention of Cancer
Michael B. Sporn,Nanjoo Suh +1 more
TL;DR: The importance of developing totally new classes of chemopreventive agents is stressed, with particular emphasis on the potential usefulness of new synthetic triterpenoids derived from naturally occurring molecules.
Book ChapterDOI
Perspectives on cancer chemoprevention research and drug development.
TL;DR: This chapter focuses on the nature of carcinogenesis and provides an overview of the progress in this field, and presents successful strategies in chemoprevention, and describes a strategy for effectively using surrogate end points in definingChemopreventive efficacy.
Journal Article
Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice.
Zhi Y. Wang,Mou-Tuan Huang,You-Rong Lou,Jian-Guo Xie,Kenneth R. Reuhl,Harold L. Newmark,Chi-Tang Ho,Chung S. Yang,Allan H. Conney +8 more
TL;DR: Administration of black tea was comparable to green tea as an inhibitor of UVB-induced skin carcinogenesis in DMBA-initiated SKH-1 mice.
Journal ArticleDOI
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract
TL;DR: The in vitro inhibitory effect of Beta vulgaris (beet) root extract on Epstein-Barr virus early antigen induction using Raji cells revealed a high order of activity compared to capsanthin, cranberry, red onion skin and short and long red bell peppers, suggesting that beetroot ingestion can be one of the useful means to prevent cancer.
Book ChapterDOI
Natural food colours
TL;DR: In this paper, the authors discuss the factors affecting the stability of these and other permitted natural colours and their commercial applications and discuss their application in the food industry, including beetroot, turmeric and carmine.