Journal ArticleDOI
Clinical practice guidelines for chronic cardiovascular disorders: a roadmap for the future.
Elliott M. Antman,Mariell Jessup +1 more
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TLDR
Clinicians want to provide their patients with the best possible advice with respect to the management of cardiovascular risk, often implementing evidence-based clinical practice guidelines designed to improve health outcomes.Abstract:
The World Health Organization lists ischemic heart disease and stroke as the top 2 leading causes of death worldwide in 2011, responsible for 7 million and 6.2 million deaths, respectively.1 The concept of risk factors for atherosclerotic cardiovascular disease (CVD) was introduced in 1961, based on epidemiologic observations from the Framingham Heart Study. Hypertension and abnormal blood lipid levels were key risk factors shown to be associated with an increased risk of angina pectoris, myocardial infarction, and sudden cardiac death; later, stroke was identified as an important outcome as well, especially in women and racial/ethnic subgroups. Accordingly, clinicians want to provide their patients with the best possible advice with respect to the management of cardiovascular risk, often implementing evidence-based clinical practice guidelines designed to improve health outcomes.read more
Citations
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Journal ArticleDOI
Persimmon (Diospyros kaki) fruit: hidden phytochemicals and health claims.
Masood Sadiq Butt,M. Tauseef Sultan,Mahwish Aziz,Ambreen Naz,Waqas Ahmed,Naresh Kumar,Muhammad Imran +6 more
TL;DR: In this article, a review of persimmon fruit with special reference to its phytochemistry and associated health claims is presented, where the role of its certain bioactive molecules like proanthocyanidin, carotenoids, tannins, flavonoids, anthocyanin, catechin, etc. is highlighted.
Journal ArticleDOI
[The problem of safety of lipid-lowering therapy].
TL;DR: The author concluded that despite the high safety of statins acknowledged by all international cardiological societies, practicing doctors still continue unreasonably cancel statins, exposing the patient under even greater danger.
Journal ArticleDOI
The promise of lifestyle for cardiovascular health: time for implementation.
TL;DR: Akesson et al. as discussed by the authors investigated how five basic lifestyle factors relate to the risk of a first myocardial infarction (MI) in a large, community-based cohort of generally healthy Swedish men.
Journal Article
The Concept of Functional Foods and Functional Farming (4 F) in the Prevention of Cardiovascular Diseases: A Review of Goals from 18th World Congress of Clinical Nutrition
Rochika Singh,Toru Takahashi,Sergey Shastun,Galal Elkilany,Krasimira Hristova,Abdulla Shehab,Ekasit Onsaard,Wiriya Phomkong,Hilton Chaves,Mukta Singh,Ratan K Srivastava,Munushi Srivastav,R. G. Singh +12 more
TL;DR: This communication finds that this is an opportunity to develop an international consensus on how to approach the prevention of malnutrition, CVDs and other chronic diseases, so that there is no increase in human susceptibility to these diseases.
Book ChapterDOI
Dietary Sugar Intake and Risk of Noncommunicable Diseases
Viliam Mojto,Ram B. Singh,Anna Gvozdjáková,Mária Mojtová,Jarmila Kucharská,Poonam Jaglan,O Vancova,Toru Takahashi +7 more
TL;DR: There is a need to educate the population about the health hazards associated with sugar consumption and the sugar-sweetened beverages are a marker of an unhealthy lifestyle and their drinkers consume more calories, exercise less, smoke more, and have a poor dietary pattern.
References
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Journal ArticleDOI
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.
Colin Baigent,L Blackwell,Jonathan Emberson,Lisa Holland,Christina Reith,Neeraj Bhala,Richard Peto,Elizabeth H Barnes,Anthony C Keech,John Simes,Rory Collins +10 more
TL;DR: Further reductions in LDL cholesterol safely produce definite further reductions in the incidence of heart attack, of revascularisation, and of ischaemic stroke, with each 1·0 mmol/L reduction reducing the annual rate of these major vascular events by just over a fifth.
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Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
TL;DR: All the classes of blood pressure lowering drugs have a similar effect in reducing CHD events and stroke for a given reduction in blood pressure, indicating that the benefit is explained by blood pressure reduction itself.
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Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women’s Health Initiative Randomized Trials
JoAnn E. Manson,Rowan T. Chlebowski,Marcia L. Stefanick,Aaron K. Aragaki,Jacques E. Rossouw,Ross L. Prentice,Garnet L. Anderson,Barbara V. Howard,Cynthia A. Thomson,Andrea Z. LaCroix,Jean Wactawski-Wende,Rebecca D. Jackson,Marian C. Limacher,Karen L. Margolis,Sylvia Wassertheil-Smoller,Shirley A.A. Beresford,Jane A. Cauley,Charles B. Eaton,Margery Gass,Judith Hsia,Karen C. Johnson,Charles Kooperberg,Lewis H. Kuller,Cora E. Lewis,Simin Liu,Lisa W. Martin,Judith K. Ockene,Mary Jo O'Sullivan,Lynda H. Powell,Michael S. Simon,Linda Van Horn,Mara Z. Vitolins,Robert B. Wallace +32 more
TL;DR: Most risks and benefits dissipated postintervention, although some elevation in breast cancer risk persisted during cumulative follow-up and the 2 WHI hormone therapy trials do not support use of this therapy.
Journal ArticleDOI
Transforming Clinical Trials in Cardiovascular Disease: Mission Critical for Health and Economic Well-being
TL;DR: The National Center for Advancing Translational Sciences (NCATS) is dedicated to catalyzing innovative methods and technologies to enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of merchandiseases and conditions.
Journal ArticleDOI
Efficacy and safety of more intensive lowering of LDL cholesterol
TL;DR: The hypothesis that pravastatin therapy was associated with an increasing risk of cancer as age increased was generated and test this hypothesis with the available individual data from the CCT Collaboration would be extremely valuable.
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