Journal ArticleDOI
Controlling factors in the synthesis of cucurbituril and its homologues.
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TLDR
A wide range of reaction conditions are examined that include the effects of acid type, acid concentration, reactant concentrations, and temperature to both probe the mechanism and optimize the yields of isolated cucurbit[n]urils, where n = 5-10.Abstract:
The acid-catalyzed synthesis of cucurbit[n]urils from formaldehyde and glycoluril is poorly understood. In this paper, we examine a wide range of reaction conditions that include the effects of acid type, acid concentration, reactant concentrations, and temperature to both probe the mechanism and optimize the yields of isolated cucurbit[n]urils, where n = 5−10. A mechanism for the formation of these cucurbit[n]urils is presented. Individual cucurbit[n]urils were unambiguously identified in reaction mixtures using ESMS and 13C NMR.read more
Citations
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Journal ArticleDOI
Cinnamaldehyde–cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity
Bayan Al Tbakhi,Hamdi Nsairat,Walhan Alshaer,Abdulfattah Al-Kadash,Wissam Helal,Lubna R. Alrawashdeh,Anthony I. Day,Khaleel I. Assaf,Rola Hassouneh,Fadwa Odeh,Abeer Al Bawab +10 more
TL;DR: This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes and their resulting antitumor activity.
Journal ArticleDOI
Thermodynamics of Pillararene•Guest Complexation: Blinded Dataset for the SAMPL9 Challenge.
TL;DR: In this article , a water soluble pillararene host (WP6) and a panel of hydrophobic cationic guests (G1 - G20) were investigated by a combination of 1H NMR spectroscopy and isothermal titration calorimetry in phosphate buffered saline.
Journal ArticleDOI
Tuning thermal gelling behavior of N -isopropylacrylamide based copolymer through introducing cucurbit[8]uril ternary complex on side-chain
TL;DR: In this article, an N-isopropylacrylamide (NIPAM) based thermo-sensitive copolymer with naphthyl (Np) on its side chain was designed and a positive-charged side-chain ternary complex was formed with cucurbit[8]uril (CB[8]) and methylviologen (MV2+) via CB[8]-enhanced intermolecular charge transfer (CT) interaction.
Journal ArticleDOI
Controlled Encapsulation and Release of an Organic Guest in the Cavity of α,α′,δ,δ′‐Tetramethylcucurbit[6]uril
Journal ArticleDOI
Complexation of biologically essential (mono- and divalent) metal cations to cucurbiturils: a DFT/SMD evaluation of the key factors governing the host─guest recognition
Nikoleta Kircheva,Stefan Dobrev,Lyubima Dasheva,Iskra Z. Koleva,Valya Nikolova,Silvia Angelova,Todor Dudev +6 more
TL;DR: DFT molecular modeling has been employed in order to investigate the interactions of biologically essential metal cations to cucurbit[n]urils and evaluate the major determinants shaping the process and shed light on the mechanism of host–guest recognition.
References
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Journal ArticleDOI
I. Ueber Condensationsproducte aus Glycoluril und Formaldehyd
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An efficient, enantioselective synthesis of the taxol side chain
TL;DR: Synthese de la chaine du taxol a partir du phenylacetylene avec comme etapes-cle une epoxydation asymetrique et la scission regioselective de l'epoxyde as mentioned in this paper.
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A Molecular Bowl with Metal Ion as Bottom: Reversible Inclusion of Organic Molecules in Cesium Ion Complexed Cucurbituril
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Cucurbituril as a ligand for the complexation of cations in aqueous solutions
TL;DR: The complex formation of the ligand cucurbituril with alkaline cations and other cations have been studied by means of solubility measurements in the presence of the salts in aqueous solutions at 25 °C.
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Host–guest complexes of cucurbituril with the 4-methylbenzylammonium lon, alkali-metal cations and NH4+
TL;DR: In this article, the existence of two different complexes of cucurbituril with 4-methylbenzylammonium ions was reported. But the 1 : 1 stability constants were not reported for the 2 : 1 complexes with different cations.