Journal ArticleDOI
Controlling factors in the synthesis of cucurbituril and its homologues.
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TLDR
A wide range of reaction conditions are examined that include the effects of acid type, acid concentration, reactant concentrations, and temperature to both probe the mechanism and optimize the yields of isolated cucurbit[n]urils, where n = 5-10.Abstract:
The acid-catalyzed synthesis of cucurbit[n]urils from formaldehyde and glycoluril is poorly understood. In this paper, we examine a wide range of reaction conditions that include the effects of acid type, acid concentration, reactant concentrations, and temperature to both probe the mechanism and optimize the yields of isolated cucurbit[n]urils, where n = 5−10. A mechanism for the formation of these cucurbit[n]urils is presented. Individual cucurbit[n]urils were unambiguously identified in reaction mixtures using ESMS and 13C NMR.read more
Citations
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pH and Glutathione Dual-Responsive Dynamic Cross-Linked Supramolecular Network on Mesoporous Silica Nanoparticles for Controlled Anticancer Drug Release
TL;DR: Good release performance toward doxorubicin hydrochloride (DOX) was achieved under the simulative tumor intracellular environment and the DOX-loaded hybrid nanomaterials displayed apparent cell-growth inhibition effects to cancer cell lines, as evidenced by MTT assay and confocal laser scanning microscopy.
Journal ArticleDOI
Sandwich-type tetranuclear lanthanide complexes with cucurbit[6]uril: from molecular compounds to coordination polymers
Olga A. Gerasko,E. A. Mainicheva,Marina I. Naumova,Marco Neumaier,Manfred M. Kappes,S. Lebedkin,Dieter Fenske,Vladimir P. Fedin +7 more
TL;DR: Sandwich-type lanthanide complexes with macrocyclic ligand cucurbit[6]uril were synthesized under hydrothermal conditions from aqueous solutions of Lanthanide(III) bromides, CB[6], and 4-cyanopyridine for the first time as precursors for the synthesis of lanthanides-silver heterometallic coordination polymers.
Journal ArticleDOI
Unusual Electrochemical Properties of the Inclusion Complexes of Ferrocenium and Cobaltocenium with Cucurbit[7]uril
Winston Ong,Angel E. Kaifer +1 more
TL;DR: Ferrocenium and cobaltocenium form highly stable 1:1 inclusion complexes with the host cucurbit[7]uril as discussed by the authors, and from electronic absorption spectroscopic data the association equilibrium constants for both complexes were found to be larger than 106 L/mol.
Journal ArticleDOI
Synthesis and separation of cucurbit[n]urils and their derivatives
Hang Cong,Xing Long Ni,Xin Xiao,Ying Huang,Qian-Jiang Zhu,Sai-Feng Xue,Zhu Tao,Leonard F. Lindoy,Gang Wei +8 more
TL;DR: This review surveys synthetic procedures for obtaining cucurbit[n]urils and their substituted derivatives together with the separation and purification of these remarkable compounds.
Journal ArticleDOI
Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications
Alexandra I. Lazar,Frank Biedermann,Kamila R. Mustafina,Khaleel I. Assaf,Andreas Hennig,Werner M. Nau +5 more
TL;DR: Fluorescence displacement titrations and isothermal titration calorimetry provided up to nanomolar binding affinities in aqueous solution for these hydrophobic target molecules, exceeding the values of known synthetic receptors.
References
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Journal ArticleDOI
I. Ueber Condensationsproducte aus Glycoluril und Formaldehyd
Journal ArticleDOI
An efficient, enantioselective synthesis of the taxol side chain
TL;DR: Synthese de la chaine du taxol a partir du phenylacetylene avec comme etapes-cle une epoxydation asymetrique et la scission regioselective de l'epoxyde as mentioned in this paper.
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A Molecular Bowl with Metal Ion as Bottom: Reversible Inclusion of Organic Molecules in Cesium Ion Complexed Cucurbituril
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Cucurbituril as a ligand for the complexation of cations in aqueous solutions
TL;DR: The complex formation of the ligand cucurbituril with alkaline cations and other cations have been studied by means of solubility measurements in the presence of the salts in aqueous solutions at 25 °C.
Journal ArticleDOI
Host–guest complexes of cucurbituril with the 4-methylbenzylammonium lon, alkali-metal cations and NH4+
TL;DR: In this article, the existence of two different complexes of cucurbituril with 4-methylbenzylammonium ions was reported. But the 1 : 1 stability constants were not reported for the 2 : 1 complexes with different cations.