Convergent validity of the electronic frailty index
Caroline Brundle,Anne Heaven,Lesley Brown,Elizabeth Teale,John Young,Robert West,Andrew Clegg +6 more
Reads0
Chats0
TLDR
Evidence is provided for convergent validity of the eFI, a core component of test validity, in a multi-site UK community-based cohort study using data from the Community Ageing Research 75+ cohort.Abstract:
Background: the electronic frailty index (eFI) has been developed and validated using routine primary care electronic health record data. The focus of the original big data study was on predictive validity as a form of criterion validation. Convergent validity is a subtype of construct validity and considered a core component of the validity of a test.
Objective: to investigate convergent validity between the eFI and research standard frailty measures.
Design: cross-sectional validation study using data from the Community Ageing Research 75+ (CARE 75+) cohort.
Setting: multi-site UK community-based cohort study.
Subjects: three hundred fifty-three community-dwelling older people (median age 80 years, IQR 77–84), excluding care home residents and people in the terminal stage of life. Median eFI score of participants was 0.22 (IQR 0.14–0.31).
Methods: convergent validities between the eFI and: a research standard frailty index (FI); the phenotype model of frailty; Clinical Frailty Scale (CFS) and Edmonton Frail Scale were assessed using scatter plots and Spearman’s rank tests to estimate correlation coefficients (Spearman’s rho, ρ) and 95% confidence intervals.
Results: results indicate strong correlation between the eFI and both the research standard FI (ρ = 0.68, 95% CI 0.62–0.74) and Edmonton Frail Scale (ρ = 0.63, 95% CI 0.57–0.69). There was evidence for moderate correlation between the eFI and both the CFS (ρ = 0.59, 95% CI 0.49–0.65) and phenotype model (ρ = 0.51, 95% CI 0.42–0.59).
Conclusions: This study provides evidence for convergent validity of the eFI, a core component of test validity.read more
Citations
More filters
Journal ArticleDOI
Age-related deficit accumulation and the diseases of ageing.
TL;DR: Quantifying the contribution of age-related deficit accumulation in clinical and preclinical samples offers a powerful new tool for understanding mechanisms of age -related disease.
Journal ArticleDOI
Global frailty: The role of ethnicity, migration and socioeconomic factors.
TL;DR: The evidence suggests frailty is a manifestation of lifetime environmental exposure to adversity and risk accumulation, and can be attenuated in migrants with improvements in integration, citizenship status, and access to healthcare.
Journal ArticleDOI
Recurrent Measurement of Frailty Is Important for Mortality Prediction: Findings from the North West Adelaide Health Study.
Mark Q. Thompson,Mark Q. Thompson,Olga Theou,Olga Theou,Olga Theou,Graeme Tucker,Robert J. Adams,Renuka Visvanathan,Renuka Visvanathan +8 more
TL;DR: The relationship between frailty status (at baseline and follow-up) and mortality using both the frailty phenotype (FP) and frailty index (FI) was determined.
Journal ArticleDOI
Frailty and depression predict instrumental activities of daily living in older adults: A population-based longitudinal study using the CARE75+ cohort.
Peter A. Coventry,Dean McMillan,Andrew Clegg,Lesley Brown,Christina M. van der Feltz-Cornelis,Simon Gilbody,Shehzad Ali,Shehzad Ali +7 more
TL;DR: Frailty and depression are independently associated with reduced independence in instrumental activities of daily living and interacts with frailty to further reduce independence for mild to moderately frail individuals, suggesting that clinical management of frailty should integrate physical and mental health care.
Journal ArticleDOI
Construction of the secondary care administrative records frailty (SCARF) index and validation on older women with operable invasive breast cancer in England and Wales: a cohort study
Yasmin Jauhari,Melissa Gannon,David Dodwell,Kieran Horgan,Karen Clements,Jibby Medina,Carmen Tsang,Thompson G. Robinson,Sarah Shuk-Kay Tang,Ruth Pettengell,David A Cromwell +10 more
TL;DR: The SCARF index provides a simple and consistent method to identify frailty in population level data and could help describe differences in breast cancer treatments and outcomes.
References
More filters
Journal ArticleDOI
Frailty in Older Adults Evidence for a Phenotype
Linda P. Fried,Catherine M. Tangen,Jeremy D. Walston,Anne B. Newman,Calvin H. Hirsch,John S. Gottdiener,Teresa E. Seeman,Russell P. Tracy,Willem J. Kop,B Gregory Burke,Mary Ann McBurnie +10 more
TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
Journal Article
Cardiovascular Health Study Collaborative Research Group : Frailty in older adults : evidence for a phenotype
Journal ArticleDOI
Frailty in elderly people
TL;DR: Developing more efficient methods to detect frailty and measure its severity in routine clinical practice would greatly inform the appropriate selection of elderly people for invasive procedures or drug treatments and would be the basis for a shift in the care of frail elderly people towards more appropriate goal-directed care.
Journal ArticleDOI
A global clinical measure of fitness and frailty in elderly people
Kenneth Rockwood,Xiaowei Song,Chris MacKnight,Howard Bergman,David B. Hogan,Ian McDowell,Arnold Mitnitski +6 more
TL;DR: The ability of the Clinical Frailty Scale to predict death or need for institutional care, and correlated the results with those obtained from other established tools are determined.
Journal ArticleDOI
Frailty Consensus: A Call to Action
John E. Morley,Bruno Vellas,G. Abellan Van Kan,Stefan D. Anker,Juergen M. Bauer,Roberto Bernabei,Matteo Cesari,Wm. Cameron Chumlea,Wolfram Doehner,Jonathan Evans,Linda P. Fried,Jack M. Guralnik,Paul R. Katz,Theodore K. Malmstrom,Roger McCarter,Luis Miguel Francisco Gutierrez Robledo,Kenneth Rockwood,Stephan von Haehling,Maurits Vandewoude,Jeremy D. Walston +19 more
TL;DR: For the purposes of optimally managing individuals with physical frailty, all persons older than 70 years and all individuals with significant weight loss (>5%) due to chronic disease should be screened for frailty.