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Open AccessJournal ArticleDOI

COVID-19 and Obesity: Overlapping of Two Pandemics.

Maria Alessandra Gammone, +1 more
- 24 Sep 2021 - 
- pp 1-7
TLDR
In this paper, a review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related complications.
Abstract
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. Key Messages: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications.

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References
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Journal ArticleDOI

High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation.

TL;DR: The COVID‐19 pandemic is rapidly spreading worldwide, notably in Europe and North America where obesity is highly prevalent and the relation between obesity and severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has not been fully documented.
Journal ArticleDOI

Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial.

TL;DR: A multidisciplinary program aimed to reduce body weight in obese women through lifestyle changes was associated with a reduction in markers of vascular inflammation and insulin resistance.
Journal ArticleDOI

Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response

TL;DR: Adipose tissue rarefaction might lie upstream of both low AT pO2 and inflammation in obesity, and novel approaches to treat the dysfunctional AT found in obesity are suggested.
OtherDOI

Adiponectin Regulation and Function

TL;DR: Adiponectin's anti-inflammatory and anti-apoptotic properties results in protection of the vasculature, heart, lung, and colon.
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