Current status of rabies and prospects for elimination.
Anthony R. Fooks,Ashley C. Banyard,Daniel L. Horton,Nicholas Johnson,Lorraine M. McElhinney,Lorraine M. McElhinney,Alan Jackson +6 more
TLDR
The most cost-effective approach to elimination of the global burden of human rabies is to control canine rabies rather than expansion of the availability of human prophylaxis.About:
This article is published in The Lancet.The article was published on 2014-10-11 and is currently open access. It has received 372 citations till now. The article focuses on the topics: Rabies.read more
Citations
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Approved Antiviral Drugs over the Past 50 Years
TL;DR: This paper presents for the first time a comprehensive overview of antiviral drugs approved over the past 50 years, shedding light on the development of effective antiviral treatments against current and emerging infectious diseases worldwide.
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Large-scale phylogenomic analysis reveals the complex evolutionary history of rabies virus in multiple carnivore hosts.
Cécile Troupin,Laurent Dacheux,Marion Tanguy,Claude Sabeta,Hervé Blanc,Christiane Bouchier,Marco Vignuzzi,Sebastián Duchêne,Edward C. Holmes,Hervé Bourhy +9 more
TL;DR: Compared evolutionary rates and selection pressures in viruses sampled from multiple primary host shifts that occurred on various continents, there is no clear evidence that dog RABV has jumped to various wildlife species from the order Carnivora, and some host shifts were associated with increases in evolutionary rate, implying that changes in host species can have important impacts on evolutionary dynamics.
Journal ArticleDOI
Global research priorities for infections that affect the nervous system
Chandy C. John,Hélène Carabin,Silvia M. Montano,Paul Bangirana,Joseph R. Zunt,Phillip K. Peterson +5 more
TL;DR: Research in these areas, accompanied by efforts to implement promising technologies and therapies, could substantially decrease the morbidity and mortality of infections affecting the nervous system in low- and middle-income countries.
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Plant-based vaccines for animals and humans: recent advances in technology and clinical trials.
TL;DR: This review discusses plant engineering technologies and regulations relevant to the development of plant-based vaccines and provides an overview of human and animal vaccines currently under clinical trials.
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Lyssaviruses and bats: emergence and zoonotic threat.
TL;DR: The detection of lyssaviruses within different bat species is reviewed and what is understood regarding their maintenance and transmission following both experimental and natural infection is overview.
References
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Journal ArticleDOI
Handbook of Physiology.
TL;DR: This is the first volume of the proposed many-sectioned "Handbook" in which the American Physiological Society intends to present comprehensively the entire field of physiology.
Journal ArticleDOI
5'-Triphosphate RNA Is the Ligand for RIG-I
Veit Hornung,Jana M. Ellegast,Sarah Kim,Krzysztof Brzózka,Andreas Jung,Hiroki Kato,Hendrik Poeck,Shizuo Akira,Karl-Klaus Conzelmann,Martin Schlee,Stefan Endres,Gunther Hartmann +11 more
TL;DR: It is demonstrated that the 5′-triphosphate end of RNA generated by viral polymerases is responsible for retinoic acid–inducible protein I (RIG-I)–mediated detection of RNA molecules in viruses known to be detected by MDA-5 such as the picornaviruses.
Journal ArticleDOI
Re-evaluating the burden of rabies in Africa and Asia
Darryn L. Knobel,Sarah Cleaveland,Paul G. Coleman,Eric M. Fèvre,Martin I. Meltzer,M. Elizabeth G. Miranda,Alexandra Shaw,Jakob Zinsstag,François-Xavier Meslin +8 more
TL;DR: Rabies remains an important yet neglected disease in Africa and Asia, and disparities in the affordability and accessibility of post-exposure treatment and risks of exposure to rabid dogs result in a skewed distribution of the disease burden across society.
Journal ArticleDOI
Survival after Treatment of Rabies with Induction of Coma
Rodney E. Willoughby,Kelly S. Tieves,George M. Hoffman,Nancy S. Ghanayem,Catherine Amlie-Lefond,Michael J. Schwabe,Michael J. Chusid,Charles E. Rupprecht +7 more
TL;DR: The survival of a 15-year-old girl in whom clinical rabies developed one month after she was bitten by a bat is reported, and treatment included induction of coma while a native immune response matured.
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Katie Hampson,Laurent Coudeville,Tiziana Lembo,Maganga Sambo,Alexia Kieffer,Michaël Attlan,Jacques Barrat,Jesse D. Blanton,Deborah J. Briggs,Sarah Cleaveland,Peter Costa,Conrad M. Freuling,Elly Hiby,Lea Knopf,Fernando Leanes,François-Xavier Meslin,A. E. Metlin,Mary Elizabeth Miranda,Thomas Müller,Louis Hendrik Nel,Sergio Recuenco,Charles E. Rupprecht,Charles E. Rupprecht,Carolin L. Schumacher,Louise H. Taylor,Marco Antonio Natal Vigilato,Jakob Zinsstag,Jonathan Dushoff +27 more