Decoding Post-Translational Modification Crosstalk With Proteomics.
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TLDR
In this paper, the authors provide an overview of the basic modes of PTM crosstalk, the proteomic methods to elucidate PTM co-stalk and approaches that can inform about the functional consequences.About:
This article is published in Molecular & Cellular Proteomics.The article was published on 2021-01-01 and is currently open access. It has received 65 citations till now. The article focuses on the topics: Crosstalk (biology).read more
Citations
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Deciphering combinatorial post-translational modifications by top-down mass spectrometry.
TL;DR: Top-down analysis of intact proteins, termed the top-down approach, offers the potential to map protein sequences and localize multiple PTMs on each protein, providing the most comprehensive cataloging of proteoforms as discussed by the authors .
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FAIMS Enhances the Detection of PTM Crosstalk Sites
TL;DR: An enrichment-free, label-free proteomics method that utilizes high-field asymmetric ion mobility spectrometry (FAIMS) to enhance the detection of PTM crosstalk and envisage LC-FAIMs-MS/MS to play an important role in expanding the repertoire of multi-PTM identifications.
Journal ArticleDOI
The evolution of post-translational modifications.
TL;DR: In this paper , the authors review advances made in the past two years towards understanding the evolution of PTMs and their associated enzymes, and the true fraction of PTM sites that are functional and thus subject to selection remains an open question.
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Proximity-Dependent Biotinylation Approaches to Explore the Dynamic Compartmentalized Proteome
Ugo Dionne,Anne-Claude Gingras +1 more
TL;DR: Progress made in this field is discussed and how proximity-dependent biotinylation strategies could elucidate the contributions of PTMs, such as phosphorylation, to the compartmentalization of proteins.
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Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway
TL;DR: In this article , the authors investigated the effect of trans-anethole (TA) on liver inflammation in broilers by determining the levels of inflammatory mediators in serum and liver, relative mRNA expression and protein expression of inflammatory genes in NF-κB signaling pathway.
References
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