Dendrimers: synthesis, applications, and properties
Elham Abbasi,Sedigheh Fekri Aval,Abolfazl Akbarzadeh,Morteza Milani,Hamid Tayefi Nasrabadi,Sang Woo Joo,Younes Hanifehpour,Kazem Nejati-Koshki,Roghiyeh Pashaei-Asl +8 more
TLDR
A variety of dendrimers exist, and each has biological properties such as polyvalency, self-assembling, electrostatic interactions, chemical stability, low cytotoxicity, and solubility that make them a good choice in the medical field.Abstract:
Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous, and monodisperse structure that has a typically symmetric core, an inner shell, and an outer shell. Their three traditional macromolecular architectural classes are broadly recognized to generate rather polydisperse products of different molecular weights. A variety of dendrimers exist, and each has biological properties such as polyvalency, self-assembling, electrostatic interactions, chemical stability, low cytotoxicity, and solubility. These varied characteristics make dendrimers a good choice in the medical field, and this review covers their diverse applications.read more
Citations
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Carbon nanotubes: properties, synthesis, purification, and medical applications
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References
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A new class of polymers: Starburst-dendritic macromolecules
Donald A. Tomalia,H. Baker,James R Dewald,Michael B. Hall,G. Kallos,Steven J. Martin,J. Roeck,J. Ryder,Patrick B. Smith +8 more
TL;DR: Starburst polymers as mentioned in this paper are a class of topological macromolecules which are derived from classical monomers/oligomers by their extraordinary symmetry, high branching and maximized terminal functionality density.
Journal ArticleDOI
Liposome: classification, preparation, and applications
Abolfazl Akbarzadeh,Rogaie Rezaei-Sadabady,Rogaie Rezaei-Sadabady,Soodabeh Davaran,Sang Woo Joo,Nosratollah Zarghami,Younes Hanifehpour,Mohammad Samiei,Mohammad Kouhi,Kazem Nejati-Koshki +9 more
TL;DR: This paper summarizes exclusively scalable techniques and focuses on strengths and limitations in respect to industrial applicability and regulatory requirements concerning liposomal drug formulations based on FDA and EMEA documents.
Journal ArticleDOI
Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
TL;DR: In this article, a convergent growth approach to topological macromolecules based on dendritic fragments is described, where polyether dendric fragments are prepared by starting from what will become the periphery of the molecule and progressing inward.
Journal ArticleDOI
About Dendrimers: Structure, Physical Properties, and Applications
Journal ArticleDOI
Dendrimers in biomedical applications--reflections on the field.
Sonke Svenson,Donald A. Tomalia +1 more
TL;DR: The reflections on biomedical applications of dendrimers given in this review clearly demonstrate the potential of this new fourth major class of polymer architecture and indeed substantiate the high hopes for the future of dendedrimers.
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Dendrimers in biomedical applications--reflections on the field.
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