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Journal ArticleDOI

Design and Production of Nanoparticles Formulated From Nano-Emulsion Templates-A Review

TLDR
A link between nano-emulsion formulation methods and nanoparticle generation is proposed, while at the same time bearing in mind the above-mentioned parameters for active molecule encapsulation.
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This article is published in Journal of Controlled Release.The article was published on 2008-06-24. It has received 1038 citations till now.

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Polymer-based nanocapsules for drug delivery

TL;DR: A comparative analysis is given of the size, zeta-potential, dispersion pH, shell thickness, encapsulation efficiency, active substance release, stability and in vivo and in vitro pharmacological performances, which allows establishing criteria for selecting a method for preparation of nanocapsules according to its advantages, limitations and behaviours as a drug carrier.
Journal ArticleDOI

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

TL;DR: In this critical review, insights are provided into the design and development of targeted polymeric NPs and the challenges associated with the engineering of this novel class of therapeutics are highlighted, including considerations of NP design optimization, development and biophysicochemical properties.
Journal ArticleDOI

Polymer nanoparticles: Preparation techniques and size-control parameters

TL;DR: In this paper, a review of the preparation of polymer nanoparticles and the crucial parameters involved in techniques designed to obtain the desired properties is presented, and the choice of method depends on a number of factors, such as particle size, particle size distribution, area of application, etc.
Journal ArticleDOI

Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity.

TL;DR: An overview of the current status of nanoemulsion formulation, fabrication, properties, applications, biological fate, and potential toxicity with emphasis on systems suitable for utilization within the food and beverage industry is provided.
References
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Journal ArticleDOI

The kinetics of precipitation from supersaturated solid solutions

TL;DR: In this paper, an analysis is made of the process whereby diffusion effects can cause the precipitation of grains of a second phase in a supersaturated solid solution, and the kinetics of this type of grain growth are examined in detail.
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Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.

TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
Journal ArticleDOI

Nanocapsule formation by interfacial polymer deposition following solvent displacement

TL;DR: In this paper, an attempt was made to elucidate the mechanisms of formation in terms of interfacial turbulence between two unequilibrated liquid phases involving flow, diffusion and surface tension decrease (Marangoni effect).
Journal ArticleDOI

Formation and stability of nano-emulsions

TL;DR: This review describes the principles of formation and stability of nano-emulsions, namely high energy emulsification (using homogenisers), low energy emulsion preparation, and the principle of the phase inversion temperature (PIT), and the role of the adsorbed layer thickness.
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