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Journal ArticleDOI

Development of antimicrobial and scar preventive chitosan hydrogel wound dressings.

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TLDR
The results suggest that drug loaded dressing could provide scar preventive wound healing and show good antimicrobial nature against both gram positive and gram negative bacteria.
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This article is published in International Journal of Pharmaceutics.The article was published on 2016-07-11. It has received 151 citations till now.

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Journal ArticleDOI

Functional Hydrogels as Wound Dressing to Enhance Wound Healing.

TL;DR: In this paper, a comprehensive review of the functional hydrogel as a wound dressing is presented, which summarizes the skin wound healing process and relates evaluation parameters and then reviews the advanced functions of hydrogels such as antimicrobial property, adhesion and hemostasis, anti-inflammatory and anti-oxidation, substance delivery, self-healing, stimulus response, conductivity, and the recently emerged wound monitoring feature.
Journal ArticleDOI

Chitosan based hydrogels and their applications for drug delivery in wound dressings: A review

TL;DR: Applications and structural characteristics of different types of active ingredients, such as growth factors, nanoparticles, nanostructures, and drug loaded chitosan hydrogels are summarized.
Journal ArticleDOI

A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing

TL;DR: The unique biological properties of a chitosan-based hydrogel enable it to serve as both a wound dressing and as a drug delivery system (DDS) to deliver antibacterial agents, growth factors, stem cells and so on, which could further accelerate wound healing.
Journal ArticleDOI

Hydrogel wound dressings for bioactive treatment of acute and chronic wounds

TL;DR: A variety of approaches to bioactive wound healing, such as bioactive dressing materials, use of antimicrobial agents, inclusion of biological signaling molecules like growth factors, and incorporation of seeded stem cells, are considered and critically evaluated.
Journal ArticleDOI

Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review

TL;DR: Almost all studies regarding natural compounds applications in wound healing by focusing on the chitosan-based bioactive wound dressing systems are collected, and the influence of bioactive compounds on their wound healing properties are reported.
References
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Journal ArticleDOI

Wound healing dressings and drug delivery systems: a review.

TL;DR: The requirement for formulations with improved properties for effective and accurate delivery of the required therapeutic agents and general formulation approaches towards achieving optimum physical properties and controlled delivery characteristics for an active wound healing dosage form are considered.
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Fabrication and characterization of a sponge-like asymmetric chitosan membrane as a wound dressing.

TL;DR: The results in this study indicate that the asymmetric chitosan membrane prepared could be adequately employed in the future as a wound dressing.
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Bacterial cellulose and bacterial cellulose-chitosan membranes for wound dressing applications.

TL;DR: Bacterial cellulose (BC) and bacterial cellulose-chitosan (BC-Ch) membranes were successfully produced in large scale and showed significant growth inhibition against Escherichia coli and Staphylococcus aureus and cell culture studies demonstrated that BC and BC-Ch had no cytotoxicity.
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Properties and biocompatibility of chitosan films modified by blending with PEG.

TL;DR: The biocompatibility of chitosan modified by several methods was carefully evaluated at the cellular and protein levels using different physical and biological methods and a basic theory for the modification of biomaterials is provided.
Journal ArticleDOI

pH-sensitive freeze-dried chitosan–polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery

TL;DR: Freeze-dried membranes could serve as potent candidates for antibiotic delivery in an acidic environment and had superior drug-release properties to air-d dried hydrogels.
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