Journal ArticleDOI
Development of the human cerebral cortex: Boulder Committee revisited
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Current data on the development of the human cerebral cortex is reviewed and the classical model of how the structure that makes us human is formed is updated.Abstract:
In 1970 the Boulder Committee described the basic principles of the development of the CNS, derived from observations on the human embryonic cerebrum Since then, numerous studies have significantly advanced our knowledge of the timing, sequence and complexity of developmental events, and revealed important inter-species differences We review current data on the development of the human cerebral cortex and update the classical model of how the structure that makes us human is formedread more
Citations
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Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances
TL;DR: The thesis of this Review is that the encephalopathy of prematurity is a complex amalgam of primary destructive disease and secondary maturational and trophic disturbances.
Journal ArticleDOI
The Basics of Brain Development
TL;DR: This chapter is intended to provide an overview of some very basic principles of brain development, drawn from contemporary developmental neurobiology, that may be of use to investigators from a wide range of disciplines.
Journal ArticleDOI
Evolution of the neocortex: a perspective from developmental biology
TL;DR: How novelties that make us human may have been introduced during evolution are described, based on findings in the embryonic cerebral cortex in different mammalian species.
Journal ArticleDOI
Transcriptional landscape of the prenatal human brain
Jeremy A. Miller,Songlin Ding,Susan M. Sunkin,Kimberly A. Smith,Lydia Ng,Aaron Szafer,Amanda Ebbert,Zackery L. Riley,Joshua J. Royall,Kaylynn Aiona,James M. Arnold,Crissa Bennet,Darren Bertagnolli,Krissy Brouner,Stephanie Butler,Shiella Caldejon,Anita Carey,Christine Cuhaciyan,Rachel A. Dalley,Nick Dee,Tim A. Dolbeare,Benjamin A.C. Facer,David Feng,Tim P. Fliss,Garrett Gee,Jeff Goldy,Lindsey Gourley,Benjamin W. Gregor,Guangyu Gu,Robert Howard,Jayson M. Jochim,Chihchau L. Kuan,Christopher Lau,Changkyu Lee,Felix Lee,Tracy Lemon,Phil Lesnar,Bergen McMurray,Naveed Mastan,Nerick Mosqueda,Theresa Naluai-Cecchini,Nhan Kiet Ngo,Julie Nyhus,Aaron Oldre,Eric Olson,Jody Parente,Patrick D. Parker,Sheana Parry,Allison Stevens,Mihovil Pletikos,Melissa Reding,Kate Roll,David Sandman,Melaine Sarreal,Sheila Shapouri,Nadiya V. Shapovalova,Elaine H. Shen,Nathan Sjoquist,Clifford R. Slaughterbeck,Michael W. Smith,Andy J. Sodt,Derric Williams,Lilla Zöllei,Bruce Fischl,Mark Gerstein,Daniel H. Geschwind,Ian A. Glass,Michael Hawrylycz,Robert F. Hevner,Hao Huang,Allan R. Jones,James A. Knowles,Pat Levitt,John W. Phillips,Nenad Sestan,Paul Wohnoutka,Chinh Dang,Amy Bernard,John G. Hohmann,Ed S. Lein +79 more
TL;DR: An anatomically comprehensive atlas of the mid-gestational human brain is described, including de novo reference atlases, in situ hybridization, ultra-high-resolution magnetic resonance imaging (MRI) and microarray analysis on highly discrete laser-microdissected brain regions.
Journal ArticleDOI
Normal development of brain circuits.
Gregory Tau,Bradley S. Peterson +1 more
TL;DR: To contextualize the developmental origins of a wide array of neuropsychiatric illnesses, this review describes the development and maturation of neural circuits from the first synapse through critical periods of vulnerability and opportunity to the emergent capacity for cognitive and behavioral regulation, and finally the dynamic interplay across levels of circuit organization and developmental epochs.
References
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Specification of cerebral cortical areas
TL;DR: The radial unit model provides a framework for understanding cerebral evolution, epigenetic regulation of the parcellation of cytoarchitectonic areas, and insight into the pathogenesis of certain cortical disorders in humans.
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Mode of cell migration to the superficial layers of fetal monkey neocortex.
TL;DR: Golgi and electronmicroscopic methods were used to define the shapes and intercellular relationships of cells migrating from their sites of origin near the ventricular surface across the intermediate zone to the superficial neocortical layers of the parietooccipital region in the brains of 75‐ to 97‐day monkey fetuses.
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Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
TL;DR: It is shown here that neurons are generated in two proliferative zones by distinct patterns of division, and newborn neurons do not migrate directly to the cortex; instead, most exhibit four distinct phases of migration, including a phase of retrograde movement toward the ventricle before migration to the cortical plate.
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Neurons derived from radial glial cells establish radial units in neocortex
Stephen C. Noctor,Alexander C. Flint,Tamily A. Weissman,Ryan S. Dammerman,Arnold R. Kriegstein +4 more
TL;DR: The results support the concept that a lineage relationship between neurons and proliferative radial glia may underlie the radial organization of neocortex.
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The cell biology of neurogenesis.
TL;DR: In this paper, the authors discuss how these features change during development from neuroepithelial to radial glial cells, and how this transition affects cell fate and neurogenesis.