C
Christopher Lau
Researcher at Allen Institute for Brain Science
Publications - 14
Citations - 9986
Christopher Lau is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Brain atlas & Neocortex. The author has an hindex of 10, co-authored 14 publications receiving 8244 citations. Previous affiliations of Christopher Lau include Allen Institute for Artificial Intelligence.
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Journal ArticleDOI
Genome-wide atlas of gene expression in the adult mouse brain
Ed S. Lein,Michael Hawrylycz,Nancy Ao,Mikael Ayres,Amy Bensinger,Amy Bernard,Andrew F. Boe,Mark S. Boguski,Mark S. Boguski,Kevin S. Brockway,Emi J. Byrnes,Lin Chen,Li Chen,Tsuey-Ming Chen,Mei Chi Chin,Jimmy Chong,Brian E. Crook,Aneta Czaplinska,Chinh Dang,Suvro Datta,Nick Dee,Aimee L. Desaki,Tsega Desta,Ellen Diep,Tim A. Dolbeare,Matthew J. Donelan,Hong-Wei Dong,Jennifer G. Dougherty,Ben J. Duncan,Amanda Ebbert,Gregor Eichele,Lili K. Estin,Casey Faber,Benjamin A.C. Facer,Rick Fields,Shanna R. Fischer,Tim P. Fliss,Cliff Frensley,Sabrina N. Gates,Katie J. Glattfelder,Kevin R. Halverson,Matthew R. Hart,John G. Hohmann,Maureen P. Howell,Darren P. Jeung,Rebecca A. Johnson,Patrick T. Karr,Reena Kawal,Jolene Kidney,Rachel H. Knapik,Chihchau L. Kuan,James H. Lake,Annabel R. Laramee,Kirk D. Larsen,Christopher Lau,Tracy Lemon,Agnes J. Liang,Ying Liu,Lon T. Luong,Jesse Michaels,Judith J. Morgan,Rebecca J. Morgan,Marty Mortrud,Nerick Mosqueda,Lydia Ng,Randy Ng,Geralyn J. Orta,Caroline C. Overly,Tu H. Pak,Sheana Parry,Sayan Dev Pathak,Owen C. Pearson,Ralph B. Puchalski,Zackery L. Riley,Hannah R. Rockett,Stephen A. Rowland,Joshua J. Royall,Marcos J. Ruiz,Nadia R. Sarno,Katherine Schaffnit,Nadiya V. Shapovalova,Taz Sivisay,Clifford R. Slaughterbeck,Simon Smith,Kimberly A. Smith,Bryan I. Smith,Andy J. Sodt,Nick N. Stewart,Kenda-Ruth Stumpf,Susan M. Sunkin,Madhavi Sutram,Angelene Tam,Carey D. Teemer,Christina Thaller,Carol L. Thompson,Lee R. Varnam,Axel Visel,Axel Visel,Ray M. Whitlock,Paul Wohnoutka,Crissa K. Wolkey,Victoria Y. Wong,Matthew J.A. Wood,Murat B. Yaylaoglu,Rob Young,Brian L. Youngstrom,Xu Feng Yuan,Bin Zhang,Theresa A. Zwingman,Allan R. Jones +109 more
TL;DR: An anatomically comprehensive digital atlas containing the expression patterns of ∼20,000 genes in the adult mouse brain is described, providing an open, primary data resource for a wide variety of further studies concerning brain organization and function.
Journal ArticleDOI
An anatomically comprehensive atlas of the adult human brain transcriptome
Michael Hawrylycz,Ed S. Lein,Angela L. Guillozet-Bongaarts,Elaine H. Shen,Lydia Ng,Jeremy A. Miller,Louie N. van de Lagemaat,Kimberly A. Smith,Amanda Ebbert,Zackery L. Riley,Chris Abajian,Christian F. Beckmann,Amy Bernard,Darren Bertagnolli,Andrew F. Boe,Preston M. Cartagena,M. Mallar Chakravarty,Mike Chapin,Jimmy Chong,Rachel A. Dalley,Barry Daly,Chinh Dang,Suvro Datta,Nick Dee,Tim A. Dolbeare,Vance Faber,David Feng,David R. Fowler,Jeff Goldy,Benjamin W. Gregor,Zeb Haradon,David R. Haynor,John G. Hohmann,Steve Horvath,Robert Howard,Andreas Jeromin,Jayson M. Jochim,Marty Kinnunen,Christopher Lau,Evan T. Lazarz,Changkyu Lee,Tracy Lemon,Ling Li,Yang Li,John A. Morris,Caroline C. Overly,Patrick D. Parker,Sheana Parry,Melissa Reding,Joshua J. Royall,Jay Schulkin,Pedro Adolfo Sequeira,Clifford R. Slaughterbeck,Simon Smith,Andy J. Sodt,Susan M. Sunkin,Beryl Swanson,Marquis P. Vawter,Derric Williams,Paul Wohnoutka,H. Ronald Zielke,Daniel H. Geschwind,Patrick R. Hof,Stephen M. Smith,Christof Koch,Seth G. N. Grant,Allan R. Jones +66 more
TL;DR: A transcriptional atlas of the adult human brain is described, comprising extensive histological analysis and comprehensive microarray profiling of ∼900 neuroanatomically precise subdivisions in two individuals, to form a high-resolution transcriptional baseline for neurogenetic studies of normal and abnormal human brain function.
Journal ArticleDOI
Transcriptional landscape of the prenatal human brain
Jeremy A. Miller,Songlin Ding,Susan M. Sunkin,Kimberly A. Smith,Lydia Ng,Aaron Szafer,Amanda Ebbert,Zackery L. Riley,Joshua J. Royall,Kaylynn Aiona,James M. Arnold,Crissa Bennet,Darren Bertagnolli,Krissy Brouner,Stephanie Butler,Shiella Caldejon,Anita Carey,Christine Cuhaciyan,Rachel A. Dalley,Nick Dee,Tim A. Dolbeare,Benjamin A.C. Facer,David Feng,Tim P. Fliss,Garrett Gee,Jeff Goldy,Lindsey Gourley,Benjamin W. Gregor,Guangyu Gu,Robert Howard,Jayson M. Jochim,Chihchau L. Kuan,Christopher Lau,Changkyu Lee,Felix Lee,Tracy Lemon,Phil Lesnar,Bergen McMurray,Naveed Mastan,Nerick Mosqueda,Theresa Naluai-Cecchini,Nhan Kiet Ngo,Julie Nyhus,Aaron Oldre,Eric Olson,Jody Parente,Patrick D. Parker,Sheana Parry,Allison Stevens,Mihovil Pletikos,Melissa Reding,Kate Roll,David Sandman,Melaine Sarreal,Sheila Shapouri,Nadiya V. Shapovalova,Elaine H. Shen,Nathan Sjoquist,Clifford R. Slaughterbeck,Michael W. Smith,Andy J. Sodt,Derric Williams,Lilla Zöllei,Bruce Fischl,Mark Gerstein,Daniel H. Geschwind,Ian A. Glass,Michael Hawrylycz,Robert F. Hevner,Hao Huang,Allan R. Jones,James A. Knowles,Pat Levitt,John W. Phillips,Nenad Sestan,Paul Wohnoutka,Chinh Dang,Amy Bernard,John G. Hohmann,Ed S. Lein +79 more
TL;DR: An anatomically comprehensive atlas of the mid-gestational human brain is described, including de novo reference atlases, in situ hybridization, ultra-high-resolution magnetic resonance imaging (MRI) and microarray analysis on highly discrete laser-microdissected brain regions.
Journal ArticleDOI
Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system
Susan M. Sunkin,Lydia Ng,Christopher Lau,Tim A. Dolbeare,Terri L. Gilbert,Carol L. Thompson,Michael Hawrylycz,Chinh Dang +7 more
TL;DR: The resources available at the Allen Brain Atlas are reviewed, describing each product and data type [such as in situ hybridization (ISH) and supporting histology, microarray, RNA sequencing, reference atlases, projection mapping and magnetic resonance imaging].
Journal ArticleDOI
A comprehensive transcriptional map of primate brain development
Trygve E. Bakken,Jeremy A. Miller,Songlin Ding,Susan M. Sunkin,Kimberly A. Smith,Lydia Ng,Aaron Szafer,Rachel A. Dalley,Joshua J. Royall,Tracy Lemon,Sheila Shapouri,Kaylynn Aiona,James M. Arnold,Jeffrey L. Bennett,Darren Bertagnolli,Kristopher Bickley,Andrew F. Boe,Krissy Brouner,Stephanie Butler,Emi J. Byrnes,Shiella Caldejon,Anita Carey,Shelby Cate,Mike Chapin,Jefferey Chen,Nick Dee,Tsega Desta,Tim A. Dolbeare,Nadia Dotson,Amanda Ebbert,Erich Fulfs,Garrett Gee,Terri L. Gilbert,Jeff Goldy,Lindsey Gourley,Ben W. Gregor,Guangyu Gu,Jon Hall,Zeb Haradon,David R. Haynor,Nika Hejazinia,Anna Hoerder-Suabedissen,Robert Howard,Jay Jochim,Marty Kinnunen,Ali Kriedberg,Chihchau L. Kuan,Christopher Lau,Changkyu Lee,Felix Lee,Lon T. Luong,Naveed Mastan,Ryan May,Jose Melchor,Nerick Mosqueda,Erika Mott,Kiet Ngo,Julie Nyhus,Aaron Oldre,Eric Olson,Jody Parente,Patrick D. Parker,Sheana Parry,Julie Pendergraft,Lydia Potekhina,Melissa Reding,Zackery L. Riley,Tyson Roberts,Brandon Rogers,Kate Roll,David Rosen,David Sandman,Melaine Sarreal,Nadiya V. Shapovalova,Shu Shi,Nathan Sjoquist,Andy J. Sodt,Robbie Townsend,Lissette Velasquez,Udi Wagley,Wayne Wakeman,Cassandra White,Crissa Bennett,Jennifer Wu,R.D. Young,Brian L. Youngstrom,Paul Wohnoutka,Richard A. Gibbs,Jeffrey Rogers,John G. Hohmann,Michael Hawrylycz,Robert F. Hevner,Zoltán Molnár,John W. Phillips,Chinh Dang,Allan R. Jones,David G. Amaral,Amy Bernard,Ed S. Lein +98 more
TL;DR: A high-resolution transcriptional atlas of rhesus monkey (Macaca mulatta) brain development is described that combines dense temporal sampling of prenatal and postnatal periods with fine anatomical division of cortical and subcortical regions associated with human neuropsychiatric disease.