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Open AccessJournal ArticleDOI

Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes.

TLDR
It is demonstrated for the first time in humans that eTRF improves some aspects of cardiometabolic health and that IF's effects are not solely due to weight loss.
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This article is published in Cell Metabolism.The article was published on 2018-06-05 and is currently open access. It has received 746 citations till now. The article focuses on the topics: Weight loss & Intermittent fasting.

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Citations
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Journal ArticleDOI

Effects of Intermittent Fasting on Health, Aging, and Disease

TL;DR: Effects of Intermittent Fasting on Health and Aging evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base fasting.
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Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome

TL;DR: This TRE intervention improves cardiometabolic health for patients with metabolic syndrome receiving standard medical care including high rates of statin and anti-hypertensive use and is a potentially powerful lifestyle intervention that can be added to standard medical practice to treat metabolic syndrome.
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Circadian clocks and insulin resistance

TL;DR: In this paper, a review of the physiological links between circadian clocks, glucose metabolism and insulin sensitivity, and present current evidence for a relationship between circadian disruption and insulin resistance is presented.
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A time to fast.

TL;DR: Future research endeavors should be directed to the integration of a balanced nutritious diet with controlled meal size and patterns and periods of fasting to develop better strategies to prevent, postpone, and treat the socioeconomical burden of chronic diseases associated with aging.
References
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Journal ArticleDOI

Adverse metabolic and cardiovascular consequences of circadian misalignment

TL;DR: The findings demonstrate the adverse cardiometabolic implications of circadian misalignment, as occurs acutely with jet lag and chronically with shift work, on metabolic, autonomic, and endocrine predictors of obesity, diabetes, and cardiovascular risk.
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Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
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Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis

TL;DR: PWA is a simple and reproducible technique with which to measure PWV and AIx and may, therefore, be suitable for large-scale population and intervention studies investigating the clinical relevance of vascular stiffness.
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Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges

TL;DR: It is shown that TRF attenuated metabolic diseases arising from a variety of obesogenic diets, and that benefits were proportional to the fasting duration, and protective effects were maintained even when TRF was temporarily interrupted by ad libitum access to food during weekends.
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Impact of intermittent fasting on health and disease processes

TL;DR: The term periodic fasting (PF) is used to describe eating patterns in which individuals go extended time periods (e.g., 16-48h) with little or no energy intake, with intervening periods of normal food intake, on a recurring basis as mentioned in this paper.
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