Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
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TLDR
It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.About:
This article is published in Respiratory Medicine.The article was published on 2008-04-01 and is currently open access. It has received 542 citations till now. The article focuses on the topics: Dry-powder inhaler & Inhaler.read more
Citations
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Journal ArticleDOI
Advancements in the Design and Development of Dry Powder Inhalers and Potential Implications for Generic Development
Abhinav Ram Mohan,Qiang Wang,Sneha Dhapare,Elizabeth Bielski,Anubhav Kaviratna,Liangfeng Han,Susan Boc,Bryan Newman +7 more
TL;DR: In this paper , a review of the current understanding of the formulation and device related principles driving DPI performance, past and present research efforts to characterize these performance factors, and the implications that advances in DPI formulations and device design may present for evaluating bioequivalence (BE) for generic development.
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Adapting Inhaled Medication Practice in COPD and Asthma to Avoid Funding the Tobacco Industry
TL;DR: In this article, the authors discuss the practicalities involved in switching people with lung disease to inhaled medications that are not tobacco industry linked, which are likely to be equally effective for most patients.
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Development of an Add-On Device Using 3D Printing for the Enhancement of Drug Administration Efficiency of Dry Powder Inhalers (Accuhaler)
Kittipat Suwanpitak,Lee Yong Lim,Inderbir Singh,Pornsak Sriamornsak,Thanongsak Thepsonthi,Kampanart Huanbutta,Tanikan Sangnim +6 more
TL;DR: An add-on device for dry powder inhalers (Accuhaler) via 3D printing is developed to improve drug administration efficiency in patients with limited inspiratory capacity, including young children, the elderly, and those with chronic obstructive pulmonary disease.
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WITHDRAWN: ¿Utilizan correctamente los inhaladores los pacientes con Enfermedad Pulmonar Obstructiva Crónica del centro de Atención Primaria Antón Borja?
TL;DR: The percentage of patients with Pulmonary Obstructive Chronic Disease who doing of incorrect form the inhaler technique was determined to reflect the need for the implementation of an educational program in the Primary Care Center to teach patients to use inhaler devices.
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Inhalation Profiles Through a Dry Powder Inhaler: Relation Between Inhalation Technique and Spirometric Measures.
Agata Dorosz,Tomasz Urbankowski,Krzysztof Zieliński,Marcin Michnikowski,Rafał Krenke,Arkadiusz Moskal +5 more
TL;DR: In this article, the authors assess the relationship between spirometric measures and inhalation profiles through a low-resistance DPI, and compare parameters of those profiles between optimal and suboptimal inhalation technique type.
References
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Universities and tobacco money.
TL;DR: Nottingham University's establishment of an international centre for corporate social responsibility, with initial funding of £3.8m provided by British American Tobacco, joins a long list of universities that have accepted funding from the tobacco industry.
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Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
Violaine Giraud,Nicolas Roche +1 more
TL;DR: Misuse of pressurized metered-dose inhalers, which is mainly due to poor coordination, is frequent and associated with poorer asthma control in inhaled corticosteroid-treated asthmatics, highlighting the importance of evaluating inhalation technique and providing appropriate education in all patients.
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Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size.
TL;DR: Regional targeting of inhaled beta2-agonist to the proximal airways is more important than distal alveolar deposition for bronchodilation and can appreciably enhance inhaled drug therapy and may have implications for developing future inhaled treatments.
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Inhaled corticosteroids for asthma therapy: patient compliance, devices, and inhalation technique.
TL;DR: It is demonstrated that multiple factors may come between a prescription of an inhaled corticosteroid and the arrival of that medicine at its target organ, the lung.
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Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care.
Mathieu Molimard,Chantal Raherison,Séverine Lignot,F. Depont,Abdelilah Abouelfath,Nicholas Moore +5 more
TL;DR: The results suggest that there are differences in the handling of inhaler devices in real life in primary care that are not taken into account in controlled studies.
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Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
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