Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
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TLDR
It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.About:
This article is published in Respiratory Medicine.The article was published on 2008-04-01 and is currently open access. It has received 542 citations till now. The article focuses on the topics: Dry-powder inhaler & Inhaler.read more
Citations
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Journal ArticleDOI
DuoResp® Spiromax® adherence, satisfaction and ease of use: findings from a multi-country observational study in patients with asthma and COPD in Europe (SPRINT)
Job van der Palen,Job van der Palen,Isa Cerveri,Nicolas Roche,Dave Singh,Dave Singh,Vicente Plaza,Chelo Gonzalez,Oliver Patino,Irma Scheepstra,Guilherme Safioti,Vibeke Backer +11 more
TL;DR: Asthma and COPD patients using DuoResp Spiromax reported moderate-to-high medication adherence, were very satisfied with their inhaler and found it easy to use.
Journal ArticleDOI
Study protocol for a randomized, controlled trial comparing the efficacy of two educational interventions to improve inhalation techniques in patients with chronic obstructive pulmonary disease (COPD): TIEPOC Study.
José Leiva-Fernández,Francisca Leiva-Fernández,Rubén L Vázquez-Alarcón,Antonio García-Ruiz,Daniel Prados-Torres,Pilar Barnestein-Fonseca +5 more
TL;DR: The hypothesis is that the application of educational interventions (A or B) in patients with COPD who use inhaler therapy will increase the number of patients who perform a correct inhalation technique by at least 25%.
Journal ArticleDOI
Technical Evaluation of Soft Mist Inhaler Use in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
TL;DR: Proper use of TBS inhaler can significantly improve the symptom control of COPD patients and Healthcare providers should not only teach the patients about the drug preparation but help them use the inhaler correctly.
Journal ArticleDOI
Real-world effectiveness evaluation of budesonide/formoterol Spiromax for the management of asthma and chronic obstructive pulmonary disease in the UK
Jaco Voorham,Nicolas Roche,Hicham Benhaddi,Marianka van der Tol,Victoria Carter,Job F M van Boven,Leif Bjermer,Marc Miravitlles,David Price +8 more
TL;DR: Among UK patients with asthma and COPD, real-world use of BF Spiromax was non-inferior to BF Turbuhaler in terms of disease control, and switching to BF SpirOMax was associated with reduced exacerbations, reduced SABA use and improved treatment stability versus continuing on BF TurBuhaler.
Dissertation
Effect of Inhalation Manoeuvre Parameters In-Vitro and Ex-Vivo on the Dose Emission and the Aerodynamic Characteristics of Formoterol and Indacaterol from Marketed Dry Powder Inhalers
TL;DR: A wide range of MIFs and Vins were used to investigate the dose emission and aerodynamic characteristics of formoterol and indacaterol using the in-vitro methodology and found that increasing the Vin and MIF resulted in a significant increase in the total emitted dose (TED), the fine particle dose (FPD) and a significant decrease in the Mass median aerodynamic diameter (MMAD) over a MIF range of 28.3.
References
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Universities and tobacco money.
TL;DR: Nottingham University's establishment of an international centre for corporate social responsibility, with initial funding of £3.8m provided by British American Tobacco, joins a long list of universities that have accepted funding from the tobacco industry.
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Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
Violaine Giraud,Nicolas Roche +1 more
TL;DR: Misuse of pressurized metered-dose inhalers, which is mainly due to poor coordination, is frequent and associated with poorer asthma control in inhaled corticosteroid-treated asthmatics, highlighting the importance of evaluating inhalation technique and providing appropriate education in all patients.
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Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size.
TL;DR: Regional targeting of inhaled beta2-agonist to the proximal airways is more important than distal alveolar deposition for bronchodilation and can appreciably enhance inhaled drug therapy and may have implications for developing future inhaled treatments.
Journal ArticleDOI
Inhaled corticosteroids for asthma therapy: patient compliance, devices, and inhalation technique.
TL;DR: It is demonstrated that multiple factors may come between a prescription of an inhaled corticosteroid and the arrival of that medicine at its target organ, the lung.
Journal ArticleDOI
Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care.
Mathieu Molimard,Chantal Raherison,Séverine Lignot,F. Depont,Abdelilah Abouelfath,Nicholas Moore +5 more
TL;DR: The results suggest that there are differences in the handling of inhaler devices in real life in primary care that are not taken into account in controlled studies.
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