Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.
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TLDR
Most polyamines exist as a polyamine-RNA complex in cells under the conditions that globin synthesis is stimulated by spermine in a rabbit reticulocyte cell-free system and the amount of sPermine bound to RNA was very close to the value estimated in the cells.About:
This article is published in Journal of Biological Chemistry.The article was published on 1991-11-05 and is currently open access. It has received 321 citations till now. The article focuses on the topics: Spermine & Polyamine binding.read more
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Journal Article
The glutamate receptor ion channels
TL;DR: The cloning of cDNAs encoding glutamate receptor subunits, which occurred mainly between 1989 and 1992, stimulated the development of ionotropic glutamate receptors in the brain.
Journal ArticleDOI
Polyamines: Mysterious Modulators of Cellular Functions
Kazuei Igarashi,Keiko Kashiwagi +1 more
TL;DR: Polyamines were found to modulate protein synthesis at several different levels including stimulation of special kinds of protein synthesis, stimulation of the assembly of 30 S ribosomal subunits and stimulation of Ile-tRNA formation.
Journal ArticleDOI
The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity
TL;DR: Recent data highlighting the novel and important roles of GluR2 in synaptic function and plasticity are brought together.
Journal ArticleDOI
Modulation of cellular function by polyamines
Kazuei Igarashi,Keiko Kashiwagi +1 more
TL;DR: The major focus on this review is on the role of polyamines in protein synthesis, and effects of polyamine oxidases on B to Z conversion of DNA, transcription, phosphorylation of proteins, cell cycle progression, apoptosis and ion channels.
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Inward Rectification of Both AMPA and Kainate Subtype Glutamate Receptors Generated by Polyamine-Mediated Ion Channel Block
Derek Bowie,Mark L. Mayer +1 more
TL;DR: CA2+-permeable glutamate receptors assembled from subunits containing a GLN residue at the RNA editing site in membrane domain 2 show strong inward rectification, and analysis of the voltage dependence of whole-cell responses predicted intracellular free spermine and spermidine concentrations of 51 and 153 muM, respectively.
References
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Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Book
Molecular Cloning: A Laboratory Manual
TL;DR: Molecular Cloning has served as the foundation of technical expertise in labs worldwide for 30 years as mentioned in this paper and has been so popular, or so influential, that no other manual has been more widely used and influential.
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The Attractions of Proteins for Small Molecules and Ions
TL;DR: The number and variety of known compounrjs between proteins and small molecules are increasing rapidly and make a fascinating story as discussed by the authors, and there are many compounds of serum albumin, which was used during the war by many chemists, most of whom found at least one 6ew compound.
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A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter
TL;DR: A modification of the naphthalene-dioxane-PPO liquid scintillator has been described which will allow up to 3.0 ml of an aqueous solution to be counted as mentioned in this paper.
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Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.
TL;DR: The results indicate that the binding of any non-interacting ligand covering more than one lattice residue results in non- linear (convex downward) Scatchard plots, and the introduction of positive ligand-ligand co-operativity antagonizes this non-linearity, and eventually leads to plots of the opposite curvature.