Journal ArticleDOI
Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria.
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TLDR
The study showed the clinical history screening test for AS to be moderately sensitive, but it might be better in clinical practice, and substitution of the Rome pain criterion for the New York pain criterion is proposed.Abstract:
The New York and the Rome diagnostic criteria for ankylosing spondylitis (AS) and the clinical history screening test for AS were evaluated in relatives of AS patients and in population control subjects. The New York criterion of pain in the (dorso) lumbar spine lacks specificity, and the chest expansion criterion is too insensitive. The Rome criterion of low back pain for more than 3 months is very useful. Our study showed the clinical history screening test for AS to be moderately sensitive, but it might be better in clinical practice. As a modification of the New York criteria, substitution of the Rome pain criterion for the New York pain criterion is proposed.read more
Citations
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Switching from infliximab to once‐weekly administration of 50 mg etanercept in resistant or intolerant patients with ankylosing spondylitis: Results of a fifty‐four–week study
Fabrizio Cantini,Laura Niccoli,Maurizio Benucci,Daniela Chindamo,Carlotta Nannini,Ignazio Olivieri,Angela Padula,Carlo Salvarani +7 more
Journal ArticleDOI
Clinical, Economic, and Humanistic Burden Associated With Delayed Diagnosis of Axial Spondyloarthritis: A Systematic Review.
TL;DR: Delayed axSpA diagnosis was associated with more functional impairment, higher healthcare costs, and worse quality of life, highlighting the importance of early recognition of ax SpA to reduce extensive burden on patients and society.
Journal ArticleDOI
A five-year prospective study of spinal radiographic progression and its predictors in men and women with ankylosing spondylitis
Anna Deminger,Eva Klingberg,Mats Geijer,Jan Göthlin,Martin Hedberg,Eva Rehnberg,Hans Carlsten,Lennart T H Jacobsson,Helena Forsblad-d'Elia,Helena Forsblad-d'Elia +9 more
TL;DR: This first report on sex-specific predictors of spinal radiographic progression shows that predictors may partly differ between the sexes.
Journal ArticleDOI
Body composition, insulin, and leptin levels in patients with ankylosing spondylitis.
Ismail Sari,Tevfik Demir,Leyla Didem Kozaci,Servet Akar,Tulay Kavak,Merih Birlik,Fatos Onen,Nurullah Akkoc +7 more
TL;DR: Chronic inflammatory condition in AS may be responsible for the reduced body fat content and lower circulating leptin concentrations and Insulin levels and insulin resistance indices seem similar in patients and controls in the absence of classic vascular risk factors.
Journal ArticleDOI
Optimized peptide-MHC multimer protocols for detection and isolation of autoimmune T-cells
Garry Dolton,Efthalia Zervoudi,Cristina Rius,Aaron Wall,Hannah L. Thomas,Anna Fuller,Lorraine Yeo,Mateusz Legut,Sophie Wheeler,Meriem Attaf,Dmitriy M. Chudakov,Ernest Choy,Mark Peakman,Mark Peakman,Andrew K. Sewell +14 more
TL;DR: It is concluded that regular pMHC tetramer staining is generally unsuitable for recovering self-reactive T-cells from clinical samples and recommend the use of the optimized protocols described herein.
References
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Journal ArticleDOI
The 1982 revised criteria for the classification of systemic lupus erythematosus
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Journal ArticleDOI
Clinical history as a screening test for ankylosing spondylitis.
TL;DR: A controlled study demonstrated that the clinical history may be sensitive and specific in the differential diagnosis of ankylosing spondylitis when reliance of five specific historic features is made.
Journal ArticleDOI
The Epidemiology of Chronic Rheumatism
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Journal ArticleDOI
The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population.
TL;DR: The discriminatory value of the New York criterion of history of pain or the presence of pain at the dorsolumbar junction or in the lumbar spine was analyzed in the population and family studies and was found to be too nonspecific.
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