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Journal ArticleDOI

Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria.

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TLDR
The study showed the clinical history screening test for AS to be moderately sensitive, but it might be better in clinical practice, and substitution of the Rome pain criterion for the New York pain criterion is proposed.
Abstract
The New York and the Rome diagnostic criteria for ankylosing spondylitis (AS) and the clinical history screening test for AS were evaluated in relatives of AS patients and in population control subjects. The New York criterion of pain in the (dorso) lumbar spine lacks specificity, and the chest expansion criterion is too insensitive. The Rome criterion of low back pain for more than 3 months is very useful. Our study showed the clinical history screening test for AS to be moderately sensitive, but it might be better in clinical practice. As a modification of the New York criteria, substitution of the Rome pain criterion for the New York pain criterion is proposed.

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Journal ArticleDOI

Efficacy of infliximab in refractory ankylosing spondylitis: results of a six‐month open‐label study

TL;DR: This study confirms the remarkable efficacy of infliximab in a large group of severely affected AS patients, and almost one-third of completers were still free of relapse 4 months after the last infusion.
Journal ArticleDOI

Percentage of patients with spondyloarthritis in patients referred because of chronic back pain and performance of classification criteria: experience from the Spondyloarthritis Caught Early (SPACE) cohort

TL;DR: The inclusion criteria of the SPACE cohort yield the same high numbers of SpA patients compared with referral strategies like inflammatory back pain, HLA-B27+ or sacroiliitis, yet are easier to apply.
Journal ArticleDOI

The high prevalence of subclinical atherosclerosis in patients with ankylosing spondylitis without clinically evident cardiovascular disease.

TL;DR: Results of the present study show that patients with ankylosing spondylitis without clinically evident cardiovascular disease have a high prevalence of subclinical macrovascular disease in the form of increased carotid IMT andCarotid plaques compared to matched controls.
Journal Article

Clinical and imaging correlates of response to treatment with infliximab in patients with ankylosing spondylitis.

TL;DR: Infliximab was an effective treatment for AS in a short term trial and very good responders were distinguished from good responders by shorter duration of disease and better baseline clinimetric scores.
Journal ArticleDOI

Comparison of serum IL-1β, sIL-2R, IL-6, and TNF-α levels with disease activity parameters in ankylosing spondylitis

TL;DR: It is suggested that sIL-2R, IL-6, and TNF-α may have a role in the pathogenesis of AS and that their serum levels can be used as disease activity parameters and tools for diagnosis.
References
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Journal ArticleDOI

The 1982 revised criteria for the classification of systemic lupus erythematosus

TL;DR: The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification and showed gains in sensitivity and specificity.
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Preliminary criteria for the classification of systemic sclerosis (scleroderma)

TL;DR: A multicenter, ongoing study of early-diagnosed cases of systemic sclerosis and comparison patients with systemic lupus erythematosus, polymyositis/dermatomyositis, and Raynaud's phenomenon was conducted in order to develop classification criteria for systemic sclerosis.
Journal ArticleDOI

Clinical history as a screening test for ankylosing spondylitis.

TL;DR: A controlled study demonstrated that the clinical history may be sensitive and specific in the differential diagnosis of ankylosing spondylitis when reliance of five specific historic features is made.
Journal ArticleDOI

The Epidemiology of Chronic Rheumatism

TL;DR: The human hand is a fascinating subject, an actor of many roles and disguises: the man in miniature, revealing its owner's story, here is a book which sets out to teach us how best to examine it and is disappointing because it is only 50 per cent of the classic it might have been
Journal ArticleDOI

The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population.

TL;DR: The discriminatory value of the New York criterion of history of pain or the presence of pain at the dorsolumbar junction or in the lumbar spine was analyzed in the population and family studies and was found to be too nonspecific.
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