DatasetDOI
Faculty of 1000 evaluation for A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Reads0
Chats0
About:
The article was published on 2018-02-07. It has received 42 citations till now. The article focuses on the topics: Small RNA & Ribosome biogenesis.read more
Citations
More filters
Journal ArticleDOI
Role of tRNA-derived small RNAs(tsRNAs) in the diagnosis and treatment of malignant tumours
Mingwen Mao,Dong Ye +1 more
Journal ArticleDOI
tRF-3013b inhibits gallbladder cancer proliferation by targeting TPRG1L
Lu Zou,Yang Yang,Biyu Zhou,Weijian Li,Ke-Min Liu,Guoqiang Li,Huijie Miao,Xiaoling Song,Jia-Hua Yang,Ya-jun Geng,Maolan Li,Runfa Bao,Yingbin Liu +12 more
TL;DR: In this article , the expression and biofunction of tRNA-derived fragments (tRFs) in gallbladder cancer (GBC) have not been reported yet, and the expression of tRFs in GBC was detected by tRNA and tiRNA sequencing in gBC tissues and adjacent tissues.
Journal ArticleDOI
Non-Coding Ribonucleic Acids as Regulators of Ferroptosis in Cancer
TL;DR: It is emphasized that the regulation of ferroptosis in tumor cells by noncoding ribonucleic acids may provide a basis for future targeted cancer therapy.
Posted ContentDOI
The small RNA component of Arabidopsis phloem sap and its response to iron deficiency
TL;DR: In this paper , RNA was extracted from phloem exudates of Arabidopsis thaliana to discover sRNA that might function during iron deficiency stress, and miRNAs were defined.
Posted ContentDOI
Transcriptomic profiles of stress susceptibility and resilience in the amygdala and hippocampus
Kimberly Lp Long,Sandra E Muroy,Siamak K. Sorooshyari,Mee Jung Ko,Yanabah Jaques,Peter H. Sudmant,Daniel I. Kaufer +6 more
TL;DR: In this paper , the authors profiled the transcriptomic signatures of the dentate gyrus (DG) and basolateral nucleus of the amygdala (BLA) of rats with divergent behavioral outcomes after a single, severe stressor.
References
More filters
Journal ArticleDOI
tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA
TL;DR: The biogeneses of various tsRNAs are summarized, the emerging concepts regarding functions and mechanisms of action are presented, the potential application of ts RNAs in human diseases is highlighted, and the current problems and future research directions are put forward.
Journal ArticleDOI
miRNA-based biomarkers, therapies, and resistance in Cancer.
Boxue He,Zhenyu Zhao,Qidong Cai,Yuqian Zhang,Pengfei Zhang,Shuai Shi,Hui Xie,Xiong Peng,Wei Yin,Yongguang Tao,Xiang Wang +10 more
TL;DR: It is demonstrated that many miRNAs are engaged in the resistance of cancer therapies with their complex underlying regulatory mechanisms, whose comprehensive cognition can help clinicians and improve patient prognosis.
Journal ArticleDOI
Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis.
Cyrille Megel,Guillaume Hummel,Stéphanie Lalande,Elodie Ubrig,Valérie Cognat,Geoffrey Morelle,Thalia Salinas-Giegé,Anne-Marie Duchêne,Laurence Maréchal-Drouard +8 more
TL;DR: It is demonstrated that the Arabidopsis RNases T2, called RNS, are key players of both long and short tRFs biogenesis, and an evolutionary conserved feature of these enzymes in eukaryotes is suggested.
Journal ArticleDOI
Development of miRNA-based therapeutic approaches for cancer patients.
TL;DR: Recent progress in the development of miRNA therapeutics for the treatment of cancer patients is summarized, and delivery systems for oligonucleotide therapeutics are described.
Journal ArticleDOI
Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response.
TL;DR: The study suggests the tsRNA-mediated regulation might be crucial for the energy homeostasis and the metabolic adaptation in the cellular systems.