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Faculty of 1000 evaluation for A transfer-RNA-derived small RNA regulates ribosome biogenesis.

Richard J Maraia
About: 
The article was published on 2018-02-07. It has received 42 citations till now. The article focuses on the topics: Small RNA & Ribosome biogenesis.

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Citations
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Journal ArticleDOI

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA

Siqi Li, +2 more
- 10 May 2018 - 
TL;DR: The biogeneses of various tsRNAs are summarized, the emerging concepts regarding functions and mechanisms of action are presented, the potential application of ts RNAs in human diseases is highlighted, and the current problems and future research directions are put forward.
Journal ArticleDOI

miRNA-based biomarkers, therapies, and resistance in Cancer.

Boxue He, +10 more
- 19 Jul 2020 - 
TL;DR: It is demonstrated that many miRNAs are engaged in the resistance of cancer therapies with their complex underlying regulatory mechanisms, whose comprehensive cognition can help clinicians and improve patient prognosis.
Journal ArticleDOI

Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis.

Cyrille Megel, +8 more
- 25 Jan 2019 - 
TL;DR: It is demonstrated that the Arabidopsis RNases T2, called RNS, are key players of both long and short tRFs biogenesis, and an evolutionary conserved feature of these enzymes in eukaryotes is suggested.
Journal ArticleDOI

Development of miRNA-based therapeutic approaches for cancer patients.

Ryou-u Takahashi, +3 more
- 01 Apr 2019 - 
TL;DR: Recent progress in the development of miRNA therapeutics for the treatment of cancer patients is summarized, and delivery systems for oligonucleotide therapeutics are described.
Journal ArticleDOI

Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response.

Shiqi Luo, +6 more
- 01 Jun 2018 - 
TL;DR: The study suggests the tsRNA-mediated regulation might be crucial for the energy homeostasis and the metabolic adaptation in the cellular systems.
References
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Journal ArticleDOI

Conservation and divergence in the meiocyte srnaomes of arabidopsis, soybean, and cucumber

Jiyue Huang, +9 more
- 01 Jan 2020 - 
TL;DR: This work characterized the ms-sRNAs in soybean and cucumber, and identified three novel cucumber miRNAs, showing that the previously identified phased secondary small interfering RNA pathway involving soybean-specific miR4392 is more abundant in meiocytes.
Posted ContentDOI

SPORTS1.0: a tool for annotating and profiling non-coding RNAs optimized for rRNA- and tRNA- derived small RNAs

Junchao Shi, +4 more
- 07 Apr 2018 - 
TL;DR: The sRNA annotation pipeline optimized for rRNA- and tRNA- derived sRNAs (SPORTS1.0) is developed, which reveals that distinct signatures are present in tsRNAs and rsRNAs from different mouse cell types, and finds that compared to other sRNA species, ts RNAs bear the highest mismatch rate which is consistent with their highly modified nature.
Journal ArticleDOI

Circulating microbial small RNAs are altered in patients with rheumatoid arthritis

Michelle J. Ormseth, +13 more
- 01 Dec 2020 - 
TL;DR: Plasma microbial sRNA composition is altered in RA versus control subjects and associated with some measures of RA disease activity, but DMARD treatment does not alter microbial s RNA abundance or composition, but increased abundance of microbial sRNAs at baseline was associated with disease activity improvement at 6 months.
Journal ArticleDOI

Small RNA Sequencing Reveals Transfer RNA-derived Small RNA Expression Profiles in Retinal Neovascularization

Yingqian Peng, +8 more
- 06 Jul 2020 - 
TL;DR: This study suggests tsRNAs play key roles in the pathogenesis of RNV, indicating their therapeutic potential to treat patients with RNV and small RNA sequencing is a useful tool to identify changes in tsRNA expression, an important indicator of the progress of retinal diseases.
Posted ContentDOI

Control of noncoding RNA production and histone levels by a 5′ tRNA fragment

Ana Bošković, +3 more
- 17 Dec 2018 - 
TL;DR: Together, the data reveal a conserved mechanism for 5’ tRNA fragment control of noncoding RNA biogenesis and, consequently, in global chromatin organization.