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Fenneropenaeus indicus is protected from white spot disease by oral administration of inactivated white spot syndrome virus

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TLDR
Shrimp that survived challenges on the 5th and 10th days after cessation of IVP administration survived repeated challenges although they were sometimes positive for the presence of WSSV by a polymerase chain reaction (PCR) assay specific for W SSV.
Abstract
Fenneropenaeus indicus could be protected from white spot disease (WSD) caused by white spot syndrome virus (WSSV) using a formalin-inactivated viral preparation (IVP) derived from WSSV-infected shrimp tissue. The lowest test quantity of lyophilized IVP coated onto feed at 0.025 g(-1) (dry weight) and administered at a rate of 0.035 g feed g(-1) body weight d(-1) for 7 consecutive days was sufficient to provide protection from WSD for a short period (10 d after cessation of IVP administration). Shrimp that survived challenges on the 5th and 10th days after cessation of IVP administration survived repeated challenges although they were sometimes positive for the presence of WSSV by a polymerase chain reaction (PCR) assay specific for WSSV. These results suggest that F. indicus can be protected from WSD by simple oral administration of IVP.

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Innate Immunity, Environmental Drivers, and Disease Ecology of Marine and Freshwater Invertebrates

TL;DR: This chapter reviews known immunological mechanisms for selected phyla and finds that there are critical response pathways common to all invertebrates, including the prophenoloxidase pathway, wandering phagocytic cells, cytotoxic effector responses, and antimicrobial compounds.
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Viral disease emergence in shrimp aquaculture: origins, impact and the effectiveness of health management strategies

TL;DR: The health management strategies that have been introduced to combat the major pathogens of farmed shrimp and the reasons that disease continues to have an impact, particularly on poor, small‐holder farmers in Asia are discussed.
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Antiviral immunity in crustaceans.

TL;DR: The aim of this review is to update recent knowledge of innate immunity against viral infections in crustaceans by identifying and characterization of several antiviral molecules isolated and characterized recently from decapods.
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Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments.

TL;DR: Current knowledge of how WSSV infects and replicates in its host, and critique strategies for WSD treatment are assessed.
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Oral delivery of DNA construct using chitosan nanoparticles to protect the shrimp from white spot syndrome virus (WSSV)

TL;DR: The present study measured the changes in the level of important immunological parameters such as prophenoloxidase, superoxide dismutase and superoxide anion in hemolymph of chitosan-encapsulated VP28 DNA-treated and controls shrimp and correlated the changes with the survival percentage and protective efficacy.
References
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Journal ArticleDOI

Cellular immunity in crustaceans and the proPO system.

TL;DR: The function of the proPO system in cellular immune reactions in crustaceans and in particular the role of a protein with a molecular mass of 76 kDa, which has been shown to be involved in the communication between the different blood cell types of crayfish, are discussed.
Journal ArticleDOI

Protection of Penaeus monodon against White Spot Syndrome Virus by Oral Vaccination

TL;DR: Contrary to current assumptions that invertebrates do not have a true adaptive immune system, a specific immune response and protection can be induced in P. monodon, and these experiments open up new ways to benefit the WSSV-hampered shrimp farming industry.
Journal ArticleDOI

Hemolin: an insect-immune protein belonging to the immunoglobulin superfamily

TL;DR: Functional analyses indicate that hemolin is one of the first hemolymph components to bind to the bacterial surface, taking part in a protein complex formation that is likely to initiate the immune response.
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