Journal ArticleDOI
Gender-specific differences in clinical outcome of primary prevention implantable cardioverter defibrillator recipients
Aafke C van der Heijden,Joep Thijssen,C. Jan Willem Borleffs,Johannes B. van Rees,Ulas Höke,Enno T. van der Velde,Lieselot van Erven,Martin J. Schalij +7 more
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TLDR
Women have lower mortality and tend to experience less appropriate ICD therapy as compared with their male peers, and 21% of primary prevention ICD recipients are women.Abstract:
Objective To assess differences in clinical outcome of implantable cardioverter-defibrillator (ICD) treatment in men and women. Design Prospective cohort study. Setting University Medical Center. Patients 1946 primary prevention ICD recipients (1528 (79%) men and 418 (21%) women). Patients with congenital heart disease were excluded for this analysis. Main outcome measures All-cause mortality, ICD therapy (antitachycardia pacing and shock) and ICD shock. Results During a median follow-up of 3.3 years (25th–75th percentile 1.4–5.4), 387 (25%) men and 76 (18%) women died. The estimated 5-year cumulative incidence for all-cause mortality was 20% (95% CI 18% to 23%) for men and 14% (95% CI 9% to 19%) for women (log rank p Conclusions In clinical practice, 21% of primary prevention ICD recipients are women. Women have lower mortality and tend to experience less appropriate ICD therapy as compared with their male peers.read more
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Journal ArticleDOI
Sex Differences in Cardiac Electrophysiology and Clinical Arrhythmias: Epidemiology, Therapeutics, and Mechanisms
TL;DR: Current knowledge regarding the nature and underlying mechanisms of sex differences in basic cardiac electrophysiology and clinical arrhythmias is reviewed.
Journal ArticleDOI
Gender and outcomes after primary prevention implantable cardioverter-defibrillator implantation: Findings from the National Cardiovascular Data Registry (NCDR)
Andrea M. Russo,Stacie L. Daugherty,Frederick A. Masoudi,Yongfei Wang,Jeptha P. Curtis,Rachel Lampert +5 more
TL;DR: Among older patients receiving ICDs for primary prevention in clinical practice, women experience worse outcomes than do men, and reasons for gender differences in outcomes are poorly understood and require further investigation.
Journal ArticleDOI
The clinical course of patients with implantable cardioverter-defibrillators: Extended experience on clinical outcome, device replacements, and device-related complications.
Aafke C van der Heijden,C. Jan Willem Borleffs,Maurits S Buiten,Joep Thijssen,Johannes B. van Rees,Suzanne C. Cannegieter,Martin J. Schalij,Lieselot van Erven +7 more
TL;DR: After long-term follow-up of ICD (12 years) and CRT-D (8 years) recipients, 49% of I CD recipients and 55% of CRT’s recipients had died and appropriate defibrillator therapy was received by the majority and by almost 40% of recipients.
Journal ArticleDOI
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population
Jens Cosedis Nielsen,Yenn Jiang Lin,Márcio Jansen de Oliveira Figueiredo,Alireza Sepehri Shamloo,Alberto Alfie,Serge Boveda,Nikolaos Dagres,Darío Di Toro,Lee L. Eckhardt,Kenneth A. Ellenbogen,Carina Hardy,Takanori Ikeda,Aparna Jaswal,Elizabeth S. Kaufman,Andrew D. Krahn,Kengo Kusano,Valentina Kutyifa,Valentina Kutyifa,Han S. Lim,Gregory Y.H. Lip,Gregory Y.H. Lip,Santiago Nava-Townsend,Hui Nam Pak,Gerardo Rodriguez Diez,William H. Sauer,Anil Saxena,Jesper Hastrup Svendsen,Diego Vanegas,Marmar Vaseghi,Arthur A.M. Wilde,T. Jared Bunch,Alfred E. Buxton,Gonzalo Calvimontes,Tze Fan Chao,Lars Eckardt,Heidi Estner,Anne M. Gillis,Rodrigo Isa,Josef Kautzner,Philippe Maury,Joshua D. Moss,Gi Byung Nam,Brian Olshansky,Luis Fernando Pava Molano,Mauricio Pimentel,Mukund A. Prabhu,Wendy S. Tzou,Philipp Sommer,J. Swampillai,Alejandro Vidal,Thomas Deneke,Gerhard Hindricks,Christophe Leclercq +52 more
TL;DR: This expert consensus statement task force was set down to raise awareness of using the right risk assessment tool for a given outcome in a given population, and to provide physicians with practical proposals that may lead to rational and evidence-based risk assessment and improvement of patient care in this regard.
Journal ArticleDOI
Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy: combined registry data from eleven European countries
Christian Sticherling,Barbora Arendacká,Jesper Hastrup Svendsen,Sofieke C. Wijers,Tim Friede,Jochem Stockinger,Michael Dommasch,Béla Merkely,Rik Willems,Andrzej Lubiński,Michael Scharfe,Frieder Braunschweig,Martin Svetlosak,Christine S. Zürn,Heikki V. Huikuri,Panagiota Flevari,Caspar Lund-Andersen,Beat Schaer,Anton E. Tuinenburg,Leonard Bergau,Georg Schmidt,Gábor Széplaki,Bert Vandenberk,Emilia Kowalczyk,Christian Eick,Juhani Juntilla,David Conen,Markus Zabel,Eu-Cert-Icd Investigators +28 more
TL;DR: It is demonstrated that fewer women than men undergo ICD implantation for primary prevention after multivariate adjustment, women have a significantly lower mortality and receive fewer appropriate ICD shocks.
References
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Journal ArticleDOI
Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.
Arthur J. Moss,Wojciech Zareba,W. Jackson Hall,Helmut U. Klein,David J. Wilber,David S. Cannom,James P. Daubert,Steven L. Higgins,Mary W. Brown,Mark L. Andrews +9 more
TL;DR: In patients with a prior myocardial infarction and advanced left ventricular dysfunction, prophylactic implantation of a defibrillator improves survival and should be considered as a recommended therapy.
Journal ArticleDOI
Amiodarone or an implantable cardioverter-defibrillator for congestive Heart failure
Gust H. Bardy,Kerry L. Lee,Daniel B. Mark,Jeanne E. Poole,Douglas L. Packer,Robin Boineau,Michael J. Domanski,Charles Troutman,Jill Anderson,Steven McNulty,Nancy E. Clapp-Channing,Linda Davidson-Ray,Elizabeth S. Fraulo,Daniel P. Fishbein,Richard M. Luceri,John Ip +15 more
TL;DR: In patients with NYHA class II or III CHF and LVEF of 35 percent or less, amiodarone has no favorable effect on survival, whereas single-lead, shock-only ICD therapy reduces overall mortality by 23 percent.
Journal ArticleDOI
Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia
Arthur J. Moss,W. Jackson Hall,David S. Cannom,James P. Daubert,Steven L. Higgins,Helmut U. Klein,Joseph H. Levine,Sanjeev Saksena,Albert L. Waldo,David J. Wilber,Mary W. Brown,Moonseong Heo +11 more
TL;DR: In this article, the authors studied whether prophylactic therapy with an implanted cardioverter-defibrillator, as compared with conventional medical therapy, would improve survival in this high-risk group of patients.
Journal ArticleDOI
A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias
TL;DR: Among survivors of ventricular fibrillation or sustained ventricular tachycardia causing severe symptoms, the implantable cardioverter-defibrillator is superior to antiarrhythmic drugs for increasing overall survival.
Journal ArticleDOI
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons
Andrew E. Epstein,John P. DiMarco,Kenneth A. Ellenbogen,N.A. Mark Estes,Roger A. Freedman,Leonard S. Gettes,A. Marc Gillinov,Gabriel Gregoratos,Stephen C. Hammill,David L. Hayes,Mark A. Hlatky,L. Kristin Newby,Richard L. Page,Mark H. Schoenfeld,Michael J. Silka,Lynne W. Stevenson,Michael O. Sweeney +16 more
TL;DR: Sidney C. Smith, Jr,MD, FACC, FAHA, Chair Alice K. Jacobs, MD, F ACC,FAHA, Vice-Chair Cynthia D. Adams, RN, PhD, FAH.