Journal ArticleDOI
Genomic regions associated with fertility traits in male and female cattle: Advances from microsatellites to high-density chips and beyond
Marina R. S. Fortes,Kasey L. DeAtley,Sigrid A. Lehnert,Brian M. Burns,Antonio Reverter,Rachel Hawken,Gry Boe-Hansen,Stephen S. Moore,Milton G Thomas +8 more
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TLDR
A review of the literature to identify QTL, markers, and candidate genes that are associated with fertility across breeds to arrive at an integrated view of bovine fertility genomics and to guide the direction of future studies.About:
This article is published in Animal Reproduction Science.The article was published on 2013-09-01. It has received 47 citations till now. The article focuses on the topics: Quantitative trait locus & Polygene.read more
Citations
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Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle
Shadi Nayeri,Mehdi Sargolzaei,M. K. Abo-Ismail,M. K. Abo-Ismail,Natalie May,Stephen P. Miller,Stephen P. Miller,Flavio S Schenkel,Stephen S. Moore,Stephen S. Moore,Paul Stothard +10 more
TL;DR: The chromosomal regions and enriched pathways identified in this study confirm several previous findings and highlight new regions and pathways that may contribute to variation in production or fertility traits in dairy cattle.
Journal ArticleDOI
Pregnancy losses in cattle: potential for improvement.
TL;DR: Genomic technology will not only provide scientists with an improved understanding of the underlying biological processes involved in fertilisation and the establishment of pregnancy, but also, in the future, could identify genes responsible for improved embryo survival.
Journal ArticleDOI
Emerging role of PLAG1 as a regulator of growth and reproduction
TL;DR: Current evidence for PLAG1 as a regulator of growth and fertility is reviewed and possible endocrine mechanisms involved are discussed.
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Review: Genomics of bull fertility.
TL;DR: Considering the rapidly increasing rate of adoption of high-throughput single nucleotide polymorphism genotyping in both the US dairy and beef industries, genomic selection should be the most effective of all currently available approaches to improve male fertility.
Journal ArticleDOI
Fertility management of bulls to improve beef cattle productivity
TL;DR: This review is focused on genetic considerations for bull selection, physiology of reproductive development, breeding soundness evaluation, recent advances in assessing frozen semen, and existing and emerging uses of sexed semen in beef cattle production.
References
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Journal ArticleDOI
RNA-Seq: a revolutionary tool for transcriptomics
TL;DR: The RNA-Seq approach to transcriptome profiling that uses deep-sequencing technologies provides a far more precise measurement of levels of transcripts and their isoforms than other methods.
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Invited review: Genomic selection in dairy cattle: progress and challenges.
TL;DR: In this article, a new technology called genomic selection is revolutionizing dairy cattle breeding, which refers to selection decisions based on genomic breeding values (GEBV) and is calculated as the sum of the effects of dense genetic markers, or haplotypes of these markers, across the entire genome, thereby capturing all the quantitative trait loci (QTL) that contribute to variation in a trait.
Journal Article
Invited review: Genomic selection in dairy cattle: progress and challenges (vol 92, pg 433, 2009)
TL;DR: The reliabilities of GEBV achieved were significantly greater than the reliability of parental average breeding values, the current criteria for selection of bull calves to enter progeny test teams, and the increase in reliability is sufficiently high that at least 2 dairy breeding companies are already marketing bull teams for commercial use based on their GEBv only.
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Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner.
S. M. Galloway,Kenneth P. McNatty,Lisa Cambridge,Mika Laitinen,Jennifer L. Juengel,T. S. Jokiranta,R. J. McLaren,Kaisu Luiro,Ken G. Dodds,Grant W. Montgomery,A. E. Beattie,George H. Davis,Olli Ritvos +12 more
TL;DR: It is established that BMP15 is essential for female fertility and that natural mutations in an ovary-derived factor can cause both increased ovulation rate and infertility phenotypes in a dosage-sensitive manner.
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Mechanisms Controlling the Function and Life Span of the Corpus Luteum
TL;DR: The primary function of the corpus luteum is secretion of the hormone progesterone, which is required for maintenance of normal pregnancy in mammals, although growth hormone, prolactin, and estradiol also play a role in several species.
Related Papers (5)
Genome-wide association studies of female reproduction in tropically adapted beef cattle.
R. J. Hawken,Yuandan Zhang,Marina R. S. Fortes,Marina R. S. Fortes,Marina R. S. Fortes,E. Collis,E. Collis,W. Barris,W. Barris,N. J. Corbet,N. J. Corbet,P J Williams,P J Williams,Geoffry Fordyce,Geoffry Fordyce,R. G. Holroyd,R. G. Holroyd,J. R. W. Walkley,J. R. W. Walkley,William Barendse,William Barendse,David Johnston,K. C. Prayaga,K. C. Prayaga,Bruce Tier,Antonio Reverter,Antonio Reverter,Sigrid A. Lehnert,Sigrid A. Lehnert +28 more