Johanna Vilkki

TL;DR: Using a denser chromosome 20 marker map and exploiting linkage disequilibrium using two distinct approaches, strong evidence is provided that a chromosome segment including the gene coding for the growth hormone receptor accounts for at least part of the chromosome 20 QTL effect.

TL;DR: The G-to-A change at nt 3460 is the second mutation so far detected in LHON, and abolishes an AhaII restriction site and thus can be detected easily by RFLP analysis.

TL;DR: In this article, the authors used a denser chromosome 20 marker map and exploited linkage disequilibrium using two distinct approaches to provide strong evidence that a chromosome segment including the gene coding for the growth hormone receptor accounts for at least part of the chromosome 20 QTL effect.

TL;DR: A cattle genetic linkage map was constructed which covers more than 95 percent of the bovine genome at medium density as mentioned in this paper, and the resultant genome-wide comparative analyses indicate that while there is a greater conservation of synteny between cattle and humans compared with mice, the conservation of gene order between cows and humans is much less than would be expected from the conserving synteny.

TL;DR: The organization of a nascent international effort, the Functional Annotation of Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps of functional elements in the genomes of domesticated animal species is described.