Journal ArticleDOI
Glutamate and related amino acids in cat spinal roots, dorsal root ganglia and peripheral nerves.
A.W. Duggan,Graham A.R. Johnston +1 more
TLDR
The unique regional distribution of glutamate is consistent with the proposed role of this amino acid as an excitatory transmitter at the terminals of primary afferent fibres.Citations
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Journal ArticleDOI
Neurotransmitters in subcortical somatosensory pathways
TL;DR: This review surveys recent developments within the field of somatosensory neurotransmission, emphasizing immunocytochemical findings and increasing evidence indicates a widespread role for glutamate as a fast-acting excitatory neurotransmitter at different levels in somatoensory pathways.
Journal ArticleDOI
Selective uptake of [3H]glutamine and [3H]glutamate into neurons and satellite cells of dorsal root ganglia in vitro
I.R. Duce,I.R. Duce,P. Keen +2 more
TL;DR: It is suggested that these selective uptake processes provide supporting evidence for the existence of a neuronal-glial glutamine cycle in dorsal root ganglia and the metabolism of the two main types of dorsal rootganglion neurone is discussed.
Journal ArticleDOI
Excitatory amino acid receptors in the mammalian periphery.
TL;DR: This review summarizes the current knowledge of excitatory amino acid (EAA) receptors outside the CNS, through which EAAs may modulate various functions in peripheral organs and tissues.
Journal ArticleDOI
Localization of elevated glutaminase immunoreactivity in small DRG neurons
Charles B. Cangro,Paul M. Sweetnam,Jean R. Wrathall,Wayne B. Haser,Norman P. Curthoys,Joseph H. Neale +5 more
TL;DR: A subpopulation of sensory neurons appear to contain an elevated capacity to synthesize glutamate through the glutamine cycle and this data suggest that glutaminase immunoreactivity may be an indicator of glutamatergic function in some nerve cells.
References
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Journal ArticleDOI
Automatic recording apparatus for use in the chromatography of amino acids.
Journal ArticleDOI
The excitation and depression of spinal neurones by structurally related amino acids.
David R. Curtis,J. C. Watkins +1 more
TL;DR: A survey of the activity of compounds structurally related to both series of amino acids finds that one of them or a related substance may have excitatory transmitter function within the nervous system.
Journal ArticleDOI
Ion Exchange Chromatography of Amino Acids. A Single Column, High Resolving, Fully Automatic Procedure.
Journal ArticleDOI
Distribution of some synaptic transmitter suspects in cat spinal cord: glutamic acid, aspartic acid, gamma-aminobutyric acid, glycine and glutamine.
TL;DR: Data is presented on the distribution of glutamate, glutamine, GABA, aspartate, and glycine in dorsal and ventral roots and four spinal cord areas in the cat and the relative merits of these compounds as possible spinal excitatory or inhibitory transmitters are discussed.
Journal ArticleDOI
Properties of dorsal root unmedullated fibers on the two sides of the ganglion.
TL;DR: The argument is strongly in favor of the conclusion that among d.r.C fibers, as in other fibers, there is no cross-excitation between the axons, and the view is confirmed that the velocities of conduction in the fibers can be precisely accounted for by multiplying the diameters by a constant.