Showing papers in "Brain Research in 1985"

TL;DR: The distribution of serotonin-1 (5-HT1) receptors in the rat brain was studied by light microscopic quantitative autoradiography and the existence of 'selective' areas allowed a detailed pharmacological characterization of these sites to be made in a more precise manner than has been attained in membrane-binding studies.

TL;DR: In both sexes a decrease in SCN volume and cell number was observed in senescence (80-100 years) and the latter change was especially pronounced in patients with senile dementia of the Alzheimer type (SDAT), which suggests the presence of a structural defect in the SCN which underlies the general disturbance of biological rhythms insenescence and SDAT.

TL;DR: In unanesthetized rats the intravenous administration of low doses of ethanol produced a dose-dependent increase in the firing rate of dopaminergic neurons in the Ventral Tegmental Area, suggesting that they might be involved in the reinforcing properties of the drug.

TL;DR: HRP enters the neuraxis along the intraparenchymal microvasculature far more rapidly than can be explained on this basis, and it is postulate that a fluid circulation through the CNS occurs via paravascular pathways.

TL;DR: Measurement of EEGs from arrays of 64 electrodes chronically implanted on the olfactory bulbs of rabbits that are trained to discriminate odorant conditioned stimuli show that the odorants induce spatially distinctive amplitude patterns of neural activity.

TL;DR: Rats received unilateral injections of 6-hydroxydopamine into the medial forebrain bundle, resulting in an ipsilateral loss of striatal dopamine and of dopaminergic perikarya, and nicotine receptors appear to be located on nigrostriatal and mesolimbic dopamine neurons at the level of perikaria and terminals.

TL;DR: The origins of neuropeptide Y-like immunoreactive (NPYI) fibers in the paraventricular and dorsomedial hypothalamic nuclei of the rat were examined using immunohistochemistry and destruction of the arcuate nucleus resulted in a marked decrease of NPYI fibers ipsilaterally in these nuclei.

TL;DR: The Phaseolus lectin technique allowed the detection of the cells of origin in the paraventricular PVN, the precise position of two distinct descending axon pathways and the detailed morphology of terminal structures in midbrain, medulla oblongata and spinal cord.

TL;DR: Results indicate, at least within this area and paradigm, that differences in dendritic measures in Golgi impregnated tissue reflect differences in the number of synapses per neuron, which was highest in complex environment rats, intermediate in socially reared rats and lowest in isolates.

TL;DR: The enzyme pyruvate carboxylase is localized in astrocytes as visualized by immunofluorescence in sections of cerebellum and substantiates some recent hypotheses forAstrocyte functions, including CO2 fixation in the CNS and the replenishment of citric acid cycle intermediates by astroCytes as precursors for amino acid neurotransmitter pools.

TL;DR: A transition metal has been localized inside the synaptic vesicles of rat telencephalic boutons which make asymmetric synaptic contacts (Gray type I) and the possible involvement of vesicular zinc in synaptic transmission is discussed.

TL;DR: ‘Universite Pierre et Marie Curie (Paris VI) and Groupe de Neurobiologie Appliqute, Laboratoire de Physiologie de la Nutrition, C. R. 7, 78350 Jouy en Josas (France)’

TL;DR: Ganglion cell axons regrew to approximately their normal length (2 cm) when autologous peripheral nerve segments were inserted into the retina of adult rats for 4-18 weeks.

TL;DR: Amygdalostriatal projections have been studied in the monkey with the autoradiographic method for demonstrating axonal transport of tritiated amino acids and appear to arise mainly from the magnocellular part of the basal nucleus.

TL;DR: The localization of calcitonin gene-related peptide (CGRP) and substance P (SP) in the rat trigeminal ganglion was examined by means of the indirect immunofluorescent method and nearly all the SPI neurons contained CGRPI.

TL;DR: It is concluded that the double inhibitory striato-nigrothalamic pathway acts on VM-thalamocortical cells through a disinhibitory mechanism and the functional implication of such a mechanism is discussed.

TL;DR: The results are interpreted as evidence of mutual influences between inferotemporal and prefrontal areas, probably mediated by corticocortical connections, that are functionally important for visual discrimination and short-term memory.

TL;DR: When a substance is pressure-injected from a micropipette into the extracellular space of the brain it may either form a cavity or it may infiltrate the extracllular space and subsequent diffusion is governed by the volume fraction and tortuosity of brain tissue as well as the diffusion coefficient of the substance itself.

TL;DR: It is proposed that astrocytes respond primarily to the mechanical disruption consequent to injury and that the response promotes the restoration of the structural integrity of the lesioned tissue.

TL;DR: The data indicate that the cell bodies of origin of the mesocortical dopaminergic system are activated by stress in contrast to those DA neurons innervating the striatum, which appears to be different regulatory features than mesolimbic or nigrostriatal neurons.

TL;DR: Findings suggest that aspiny interneurons play a greater role in the integrative and functional organization of the neostriatum in the primate than in the rodent brain.

TL;DR: A monoclonal antibody labels migrating amacrine cells in late embryonic retinas and defines cell-specific gene expression in relation to migration of one subclass of CNS neurons in adult rat retina.

TL;DR: The findings indicate that the responses of these neurons would be useful in providing information on which different behavioral responses made to different faces could be based, and could thus be filters.

TL;DR: It is proposed that the rmIO may serve as a pathway for information from the unconditioned stimulus to reach the cerebellum, and as such may in fact be the essential reinforcing or teaching input for the learning of classically conditioned responses.

TL;DR: Double staining techniques using antibodies raised against choline acetyltransferase (ChAT) revealed that GAL- and ChAT-like immunoreactivities are colocalized within a subpopulation of the cholinergic neurons within the medial septum and diagonal band.

TL;DR: The duration of the phases of the cell-division cycle was investigated in ventricular cells, the mitotically active precursors of postmitotic cells that comprise the neural retina in 1-day-old mice.

TL;DR: Results suggest that the nociceptive mechanical or thermal primary afferents contain substance P or somatostatin, respectively.

TL;DR: Striatum exerts a facilitatory influence on TSD cells by releasing these neurons from the tonic inhibitory nigral influence, discussed in the light of the current knowledge on the involvement of basal ganglia in eye/head orienting movements.

TL;DR: It is reported that at least 40% of all LC neurons project to the olfactory bulb; the projection is almost 10 times greater than to any other part of the cerebral cortex.

TL;DR: The results show that a short time of conjunctive stimulation of climbing fibres and parallel fibres results in a long-lasting depression of the parallel fibre responses and that this depression can be prevented if the Purkinje cells are inhibited during the conj unctive stimulation.