Journal ArticleDOI
Glycophorin as a possible receptor for plasmodium falciparum
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TLDR
It is suggested that both glycophorins A and B are involved in parasite invasion, indicate which parts of these molecules may be involved in this process, and provide the basis for a tentative model of parasite/red-cell interactions.About:
This article is published in The Lancet.The article was published on 1982-10-30. It has received 135 citations till now. The article focuses on the topics: Glycophorin & GYPB.read more
Citations
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Blood Groups in Infection and Host Susceptibility
TL;DR: Several distinct phenotypes associated with increased host resistance to malaria are overrepresented in populations living in areas where malaria is endemic, as a result of evolutionary pressures.
Journal ArticleDOI
The relationship between blood groups and disease
TL;DR: Investigation of the migration patterns of early humans from Africa to populate the rest of the world obtained through the use of Y chromosome and mtDNA markers suggests surviving malaria is the most significant selective force affecting the expression of blood groups.
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A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites
Daniel Camus,Terence J. Hadley +1 more
TL;DR: Ierythrocytes coated with supernatant antigens from the Camp or the FCR-3 strain were invaded normally by merozoites of the homologous strain but were partially resistant to invasion bymerozoite of the heterologous strains.
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Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes.
Manoj T. Duraisingh,Tony Triglia,Stuart A. Ralph,Julian C. Rayner,John W. Barnwell,Geoffrey I. McFadden,Alan F. Cowman +6 more
TL;DR: Phenotypic variation of the PfRh protein family allows P.falciparum to exploit different patterns of receptors on the erythrocyte surface and thereby respond to polymorphisms in ery Throcyte receptors and to evade the host immune system.
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A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin A.
TL;DR: The Neu5Ac(a2,3)-Gal- determinant on O-linked tetrasaccharides of glycophorin A appear to be the preferential erythrocyte ligand for EBA-175, as demonstrated for hemagglutinins of influenza viruses.
References
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Journal ArticleDOI
Human malaria parasites in continuous culture
William Trager,James B. Jensen +1 more
TL;DR: Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and low oxygen.
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Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.
TL;DR: A new approach to study differentiation antigens by means of monoclonal xenogeneic antibodies produced by myeloma-hybrid lines in culture is described, which allows identification down to minor membrane molecules and also of antigen on small subpopulations of a heterogeneous mixture of cells.
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Demonstration von Fetalem Hamoglobin in den Erythrocyten Eines Blutausstrichs
TL;DR: In this article, a Blutfarbstoff aus Erwachsenen-Erythrocyten schneller gelost wird als aus Neugeborenenerythrocyten.