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Journal ArticleDOI

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

Richard L. Jackson, +2 more
- 01 Apr 1991 - 
- Vol. 71, Iss: 2, pp 481-539
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TLDR
Article de synthese sur les glycosaminoglycanes chez les mammiferes: proprietes et structure des proteoglycane and des proteines de liaison des glycosaminaes.
Abstract
Article de synthese sur les glycosaminoglycanes chez les mammiferes: proprietes et structure des proteoglycanes et des proteines de liaison des glycosaminoglycanes; roles dans la regulation des processus cellulaires et la regulation de l'expression des genes; interaction avec les facteurs de transcription

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Journal ArticleDOI

Order out of chaos: assembly of ligand binding sites in heparan sulfate.

TL;DR: A review of recent developments in the biosynthetic apparatus of metazoan organisms provides a resource for investigators interested in the incredible diversity and specificity of this process.
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Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions

TL;DR: It is demonstrated that membrane-associated heparan sulfate proteoglycan serves as the viral receptor for AAV type 2, and an explanation for the broad host range of AAV is provided.
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Fibroblast growth factors, their receptors and signaling.

TL;DR: FGF signaling also appears to play a role in tumor growth and angiogenesis, and autocrine FGF signaling may be particularly important in the progression of steroid hormone-dependent cancers to a hormone-independent state.
Journal ArticleDOI

Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications

TL;DR: Important considerations for designing biodegradable hydrogels for cell encapsulation are described and recent advances in material design and their applications in tissue engineering are highlighted.
Journal Article

Role of extracellular matrix assembly in interstitial transport in solid tumors.

TL;DR: It is concluded that collagen influences the tissue resistance to macromolecule transport, possibly by binding and stabilizing the glycosaminoglycan component of the ECM.
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