Journal ArticleDOI
Gold nanoparticle-based signal amplification for biosensing.
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TLDR
This article focuses on the signal amplification strategies of AuNPs in biosensing/biorecognition, more specifically, on the main optical and electrochemical detection methods that involve AuNP-based biosensing.About:
This article is published in Analytical Biochemistry.The article was published on 2011-10-01. It has received 335 citations till now.read more
Citations
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Electrochemical detection of Salmonella using an invA genosensor on polypyrrole-reduced graphene oxide modified glassy carbon electrode and AuNPs-horseradish peroxidase-streptavidin as nanotag.
Yongkang Ye,Wuwen Yan,Yaqian Liu,Shudong He,Xiaodong Cao,Xuan Xu,Haisong Zheng,Sundaram Gunasekaran +7 more
TL;DR: The rapid and sensitive electrochemical biosensor constructed to detect Salmonella using invA gene biosensor showed good regeneration ability, acceptable selectivity, repeatability and stability, which bode well as an alternative method forSalmonella screening.
Journal ArticleDOI
Electrochemical immunosensor assay (EIA) for sensitive detection of E. coli O157:H7 with signal amplification on a SG–PEDOT–AuNPs electrode interface
TL;DR: The developed electrochemical-based immunosensor might provide a useful and practical tool for E. coli O157:H7 determination and related food safety analysis and clinical diagnosis.
Journal ArticleDOI
Enhancing nanoparticle-based visible detection by controlling the extent of aggregation.
Seokwon Lim,Ok Kyung Koo,Young Sang You,Yeong Eun Lee,Minsik Kim,Pahn-Shick Chang,Dong-Hyun Kang,Jae-Hyuk Yu,Young Jin Choi,Sundaram Gunasekaran +9 more
TL;DR: A signal amplification strategy to enhance visible detection by introducing switchable linkers (SLs), which are designed to lose their function to bridge NPs in the presence of target and control the extent of aggregation is reported.
Journal ArticleDOI
Implementing atomic force microscopy (AFM) for studying kinetics of gold nanoparticle's growth
Peter A. Georgiev,Assya Bojinova,Bistra Kostova,Denitsa Momekova,Thomas Bjørnholm,Konstantin Balashev,Konstantin Balashev +6 more
TL;DR: In this article, the authors applied Atomic Force Microscopy (AFM) as a tool for studying the kinetics of gold nanoparticle growth at two different temperatures by spectrophotometric measurements and compared them with the results from AFM experimental approach.
Journal ArticleDOI
Enhancement of the sensitivity of LSPR-based CRP immunosensors by Au nanoparticle antibody conjugation
TL;DR: In this article, the authors proposed a design for a highly sensitive biosensor based on nanostructured anodical aluminum oxide (AAO) substrates, which showed high sensitivity over a wide concentration range and enabled a selective immunoassay to be performed.
References
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Book
Electrochemical Methods: Fundamentals and Applications
Allen J. Bard,Larry R. Faulkner +1 more
TL;DR: In this paper, the authors present a comprehensive overview of electrode processes and their application in the field of chemical simulation, including potential sweep and potential sweep methods, coupled homogeneous chemical reactions, double-layer structure and adsorption.
Journal ArticleDOI
Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.
TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
Journal ArticleDOI
A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials
TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
Journal ArticleDOI
Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles
TL;DR: A highly selective, colorimetric polynucleotide detection method based on mercaptoalkyloligonucleotide-modified gold nanoparticle probes is reported, which can detect about 10 femtomoles of an oligonucleotide.
Journal ArticleDOI
Nanostructures in Biodiagnostics
Nathaniel L. Rosi,Chad A. Mirkin +1 more
TL;DR: Nathaniel L. Rosi focuses on the rational assembly of DNA-modified nanostructures into larger-scale materials and their roles in biodiagnostic screening for nucleic acids.