Journal ArticleDOI
Gold nanoparticle-based signal amplification for biosensing.
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This article focuses on the signal amplification strategies of AuNPs in biosensing/biorecognition, more specifically, on the main optical and electrochemical detection methods that involve AuNP-based biosensing.About:
This article is published in Analytical Biochemistry.The article was published on 2011-10-01. It has received 335 citations till now.read more
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Noble metal nanoparticles for biosensing applications.
Gonçalo Doria,João Conde,Bruno Veigas,Letícia Giestas,Carina Almeida,Maria Assunção,João Rosa,Pedro V. Baptista +7 more
TL;DR: The use of noble metal nanoparticles for biosensing strategies is reviewed—from synthesis and functionalization to integration in molecular diagnostics platforms, with special focus on those that have made their way into the diagnostics laboratory.
Journal ArticleDOI
Nanomaterials for Sensing and Destroying Pesticides
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Current and Prospective Methods for Plant Disease Detection
Yi Fang,Ramaraja P. Ramasamy +1 more
TL;DR: The review provides a comprehensive overview of biosensors based on highly selective bio-recognition elements such as enzyme, antibody, DNA/RNA and bacteriophage as a new tool for the early identification of crop diseases.
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Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
Stefano Mariani,Valentina Robbiano,Lucanos Marsilio Strambini,Aline Debrassi,Gabriela Egri,Lars Dähne,Giuseppe Barillaro +6 more
TL;DR: An electrostatic layer-by-layer technique to functionalize a surface is reported on and this technique is demonstrated using biotinylated polymer for streptavidin detection in saliva.
References
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Journal ArticleDOI
4-(Dimethylamino)butyric acid labeling for electrochemiluminescence detection of biological substances by increasing sensitivity with gold nanoparticle amplification.
TL;DR: High biocompatibility and low cost were the main advantages of the present DMBA labeling technique over the traditional Ru(bpy)(3)2+ labeling.
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Nanoparticle enhanced surface plasmon resonance biosensing: application of gold nanorods.
TL;DR: This work paves the way to a new generation of ultra-sensitive nanoparticles-based biosensor platforms with maximized enhancement of sensitivity for ultra-fast screening and real-time detection of "hard-to-identify" biomolecules.
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Sub-Femtomolar Electrochemical Detection of DNA Hybridization Based on Latex/Gold Nanoparticle-Assisted Signal Amplification
TL;DR: A relatively simple electrostatic method for modifying submicrometer-size latex spheres with gold nanoparticles (AuNPs) based on layer-by-layer modification of the latex by polyelectrolytes that enabled a detection limit of 0.5 fM, which is equal or lower than previous voltammetric nanoparticle methods for detection of DNA hybridization.
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Enhanced photoelectrochemical method for linear DNA hybridization detection using Au-nanopaticle labeled DNA as probe onto titanium dioxide electrode.
TL;DR: The hybridization binding constant was obtained, the photocurrent decreased with increasing the concentration of target DNA, indicating that this method could be used for quantitative measurements, and the discrimination of the complementary from mismatched DNA.
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Novel colorimetric enzyme immunoassay for the detection of carcinoembryonic antigen
TL;DR: The developed method proved its potential use in clinical immunoassay of CEA, and employed gold nanoparticles as carriers of anti-CEA antibody labeled with biotin, which served as an affinity tag for streptavidin-horseradish peroxidase (streptavid in-HRP) binding.