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Gold nanoparticle-based signal amplification for biosensing.

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TLDR
This article focuses on the signal amplification strategies of AuNPs in biosensing/biorecognition, more specifically, on the main optical and electrochemical detection methods that involve AuNP-based biosensing.
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This article is published in Analytical Biochemistry.The article was published on 2011-10-01. It has received 335 citations till now.

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From a Novel

Robert Altenloh
- 01 Jan 1953 - 
Journal ArticleDOI

Noble metal nanoparticles for biosensing applications.

TL;DR: The use of noble metal nanoparticles for biosensing strategies is reviewed—from synthesis and functionalization to integration in molecular diagnostics platforms, with special focus on those that have made their way into the diagnostics laboratory.
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Current and Prospective Methods for Plant Disease Detection

TL;DR: The review provides a comprehensive overview of biosensors based on highly selective bio-recognition elements such as enzyme, antibody, DNA/RNA and bacteriophage as a new tool for the early identification of crop diseases.
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Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing

TL;DR: An electrostatic layer-by-layer technique to functionalize a surface is reported on and this technique is demonstrated using biotinylated polymer for streptavidin detection in saliva.
References
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Homogeneous detection of nucleic acids based upon the light scattering properties of silver-coated nanoparticle probes.

TL;DR: A simple, rapid, homogeneous, and sensitive detection system for DNA based on the scattering properties of silver-amplified gold nanoparticle probes, using DNA-functionalized magnetic particle probes that act as scavengers for target DNA, which can be collected via a magnetic field.
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A new amplification strategy for ultrasensitive electrochemical aptasensor with network-like thiocyanuric acid/gold nanoparticles

TL;DR: An ultrasensitive and highly specific electrochemical aptasensor for detection of thrombin based on gold nanoparticles and thiocyanuric acid is presented and is expected to have wide applications in protein monitoring and disease diagnosis.
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A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin–streptavidin system

TL;DR: Luminol functionalized gold nanoparticles were used as labels for electrochemiluminescence signal amplification and an ultrasensitive, highly selective, convenient, low cost DNA detection strategy was developed.
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Dendrimers-based DNA biosensors for highly sensitive electrochemical detection of DNA hybridization using reporter probe DNA modified with Au nanoparticles.

TL;DR: The DNA sensor not only showed low detection limit, but also exhibited excellent selectivity against two-base mismatched DNA.
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Direct electrochemistry and electrocatalysis of cytochrome c immobilized on gold nanoparticles-chitosan-carbon nanotubes-modified electrode.

TL;DR: The Cyt c/GNPs/Chit/MWNTs modified GC electrode gives an improved electrocatalytic activity towards the reduction of hydrogen peroxide (H2O2) and possesses good stability and reproducibility.
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