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Gold nanoparticle-based signal amplification for biosensing.

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TLDR
This article focuses on the signal amplification strategies of AuNPs in biosensing/biorecognition, more specifically, on the main optical and electrochemical detection methods that involve AuNP-based biosensing.
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This article is published in Analytical Biochemistry.The article was published on 2011-10-01. It has received 335 citations till now.

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A plasmonic nanosensor for lipase activity based on enzyme-controlled gold nanoparticles growth in situ.

TL;DR: A plasmonic nanosensor for lipase activity was developed based on one-pot nanoparticle growth that circumvents the problems encountered by general enzyme assays that require sophisticated instruments and complicated assembling steps and can benefit the assays of heterogeneous-catalyzed enzymes.
Journal ArticleDOI

Advancement in Salmonella Detection Methods: From Conventional to Electrochemical-Based Sensing Detection.

TL;DR: A review of Salmonella detection approaches covering their basic principles, characteristics, applications, and performances can be found in this article, where the use of a highly specific bioreceptor, such as aptamers, and the application of nanomaterials are contributing factors to these excellent characteristics.
Journal ArticleDOI

Electroactive dendrimer-encapsulated silver nanoparticles for sensing low-abundance proteins with signal amplification

TL;DR: The developed immunoassay enabled the determination of target fPSA with a wide dynamic range of 0.005–5.0 ng mL−1 and a detection limit (LOD) of 1.0 pgmL−1, and a good repeatability and intermediate reproducibility down to 7.5%.
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Triple signal amplification strategy based on size and shape transformation of ultrasmall sub-10 nm gold nanoparticles tag towards sensitivity improvement of electrochemical immunosensors

TL;DR: In this article, triple signal amplification strategy was designed to enhance the electrochemical detection sensitivity of immunosensing platform based on gold nanoparticles (AuNP) tagging, which includes the stepwise enlargement of AuNP tag.
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Time-dependent pH sensing phenomena using CdSe/ZnS quantum dots in EIS structure.

TL;DR: Time-dependent pH sensing phenomena of the core-shell CdSe/ZnS quantum dot (QD) sensors in EIS (electrolyte insulator semiconductor) structure have been investigated for the first time and the sensitivity is close to ideal Nernstian response with good linearity.
References
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Book

Electrochemical Methods: Fundamentals and Applications

TL;DR: In this paper, the authors present a comprehensive overview of electrode processes and their application in the field of chemical simulation, including potential sweep and potential sweep methods, coupled homogeneous chemical reactions, double-layer structure and adsorption.
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Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.

TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
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A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials

TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
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Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles

TL;DR: A highly selective, colorimetric polynucleotide detection method based on mercaptoalkyloligonucleotide-modified gold nanoparticle probes is reported, which can detect about 10 femtomoles of an oligonucleotide.
Journal ArticleDOI

Nanostructures in Biodiagnostics

TL;DR: Nathaniel L. Rosi focuses on the rational assembly of DNA-modified nanostructures into larger-scale materials and their roles in biodiagnostic screening for nucleic acids.
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